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Gene Expression Data
Assay Details
Assay
Reference: J:253683 Schwartz B, et al., SRF is essential for mesodermal cell migration during elongation of the embryonic body axis. Mech Dev. 2014 Aug;133:23-35
Assay type: RNA in situ
MGI Accession ID: MGI:6444165
Gene symbol: Srf
Gene name: serum response factor
Results
Specimen 1A (left): embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: embryo Present Widespread 1A (left)
TS15: branchial arch Strong Regionally restricted 1A (left) Domains of increased expression in forebrain and branchial arches.
TS15: future forebrain Strong Regionally restricted 1A (left) Domains of increased expression in forebrain and branchial arches.
TS15: 1st branchial arch maxillary-mandibular groove Strong 1A (left)
TS15: fronto-nasal process Strong 1A (left)
TS15: intermediate mesenchyme Strong 1A (left)
TS15: paraxial mesenchyme Strong Regionally restricted 1A (left) Strong expression in paraxial mesoderm in caudal region of embryo.
Specimen 1A (right): embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: unsegmented mesenchyme Present Regionally restricted 1A (right) Expression in paraxial mesoderm up to forming somitomeres.
Specimen 1B Srf flex1/+; T(s)::Cre: embryonic day 9.5; Srftm2.1Nor/Srf+, Tg(T-cre)1Gos/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: embryo mesenchyme Present 1B Srf flex1/+; T(s)::Cre
Specimen 1B Srf flex1/flex1; T(s)::Cre: embryonic day 9.5; Srftm2.1Nor/Srftm2.1Nor, Tg(T-cre)1Gos/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: embryo mesenchyme Weak Regionally restricted 1B Srf flex1/flex1; T(s)::Cre Expression reduced in all mesodermal derived tissues. Expression not detectable in posterior mesodermal tissues.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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