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Gene Expression Data
Assay Details
Assay
Reference: J:198547 Neves G, et al., The LIM Homeodomain Protein Lhx6 Regulates Maturation of Interneurons and Network Excitability in the Mammalian Cortex. Cereb Cortex. 2013 Aug;23(8):1811-23
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6442571
Gene symbol: Lhx6
Gene name: LIM homeobox protein 6
Reporter: lacZ
Antibody: anti-B-galactosidase (Promega)
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen 1B LacZ/+: postnatal; Lhx6tm1Vpa/Lhx6+ (more )
Note: Double labeled: red - Lhx6 reporter; green - Lhx6 (protein; assay MGI:6442574).
Structure Level Pattern Image Note
TS28: hippocampus CA1 Present Regionally restricted 1B LacZ/+ Expression is in cortical interneurons.
Specimen 1B LacZ/-: postnatal; Lhx6tm1Vpa/Lhx6tm2Vpa (more )
Note: Double labeled: red - Lhx6 reporter; green - Lhx6 (protein; assay MGI:6442574).
Structure Level Pattern Image Note
TS28: hippocampus CA1 Present Regionally restricted 1B LacZ/- Expression is in cortical interneurons.
Specimen 2E: postnatal week 4; Lhx6tm1Vpa/Lhx6+ (more )
Note: Double labeled: red - Lhx6 reporter; green - Lhx6 (protein; assay MGI:6442574).
Structure Level Pattern Image Note
TS28: hippocampus Present 2E
TS28: somatosensory cortex Present 2E
Specimen 2F: postnatal week 4; Lhx6tm1Vpa/Lhx6tm2Vpa (more )
Note: Double labeled: red - Lhx6 reporter; green - Lhx6 (protein; assay MGI:6442574).
Structure Level Pattern Image Note
TS28: hippocampus Present 2F Expression in this mutant is the same as in controls.
TS28: somatosensory cortex Present 2F Expression in this mutant is the same as in controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory