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Gene Expression Data
Assay Details
Assay
Reference: J:204460 Nie X, et al., Pkd1 is required for male reproductive tract development. Mech Dev. 2013 Nov-Dec;130(11-12):567-76
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6441882
Gene symbol: Smad1
Gene name: SMAD family member 1
Antibody: anti-phospho-Smad1/5
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 8A: postnatal day 1; Pkd1tm1Ggg/Pkd1+ (more )
Structure Level Pattern Image Note
TS27: efferent duct of seminal vesicle Strong 8A High level of expression in both epithelium and mesenchyme of efferent duct.
Specimen 8B: postnatal day 1; Pkd1tm1Ggg/Pkd1tm2Ggg, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: efferent duct of seminal vesicle Weak Regionally restricted 8B Ratio of cells positive for expression was significantly decreased in epithelium, but not in mesenchyme, compared to control.
Specimen 8C: postnatal day 1; Pkd1tm1Ggg/Pkd1+ (more )
Structure Level Pattern Image Note
TS27: efferent duct of seminal vesicle Strong 8C High level of expression in both epithelium and mesenchyme of epididymis.
Specimen 8D: postnatal day 1; Pkd1tm1Ggg/Pkd1tm2Ggg, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: efferent duct of seminal vesicle Weak Single cells 8D Very few expressing cells in severely dilated ducts.
Specimen 8G: postnatal day 1; Pkd1tm1Ggg/Pkd1+ (more )
Structure Level Pattern Image Note
TS27: epididymis Strong 8G
Specimen 8H: postnatal day 1; Pkd1tm1Ggg/Pkd1tm2Ggg, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: epididymis Weak Regionally restricted 8H Ratio of cells positive for expression was significantly decreased in epithelium, but not in mesenchyme, compared to control.
Specimen 8I: postnatal day 1; Pkd1tm1Ggg/Pkd1+ (more )
Structure Level Pattern Image Note
TS27: epididymis Strong 8I High level of expression in both epithelium and mesenchyme of epididymis.
Specimen 8J: postnatal day 1; Pkd1tm1Ggg/Pkd1tm2Ggg, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: epididymis Weak Regionally restricted 8J Ratio of cells positive for expression was significantly decreased in epithelium, but not in mesenchyme, compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory