About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:287785 Longmire TA, et al., Efficient derivation of purified lung and thyroid progenitors from embryonic stem cells. Cell Stem Cell. 2012 Apr 6;10(4):398-411
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6441448
Gene symbol: Nkx2-1
Gene name: NK2 homeobox 1
Reporter: GFP
Direct Detection
Results
Specimen 1C left: embryonic day 14.5; Nkx2-1tm1Ikono/Nkx2-1+ (more )
Structure Level Pattern Image Note
TS22: forebrain Present 1C left
TS22: lung Present 1C left

Specimen 1C right: embryonic day 14.5; Nkx2-1tm1Ikono/Nkx2-1+ (more )
Structure Level Pattern Image Note
TS22: lung Present 1C right Fluorescence appears in an epithelial pattern.
TS22: trachea Present 1C right Fluorescence appears in an epithelial pattern.

Specimen S1C: embryonic day 14.5; Nkx2-1tm1Ikono/Nkx2-1+ (more )
Structure Level Pattern Image Note
TS22: forebrain Present S1C
TS22: lung Present S1C

Specimen S1D: embryonic day 14.5; Nkx2-1tm1Ikono/Nkx2-1+ (more )
Structure Level Pattern Image Note
TS22: forebrain Present S1D
TS22: lung Present S1D
TS22: thyroid gland Present S1D

Specimen S1E: postnatal month 4; Nkx2-1tm1Ikono/Nkx2-1+ (more )
Structure Level Pattern Image Note
TS28: bronchiole epithelium Present S1E Expression is seen in airway epithelia.

Specimen S1F: postnatal month 4; Nkx2-1tm1Ikono/Nkx2-1+ (more )
Structure Level Pattern Image Note
TS28: alveolus epithelium Present S1F Expression is seen in alveolar epithelial type 2 cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory