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Gene Expression Data
Assay Details
Assay
Reference: J:199462 Probst S, et al., The hedgehog target Vlk genetically interacts with Gli3 to regulate chondrocyte differentiation during mouse long bone development. Differentiation. 2013 Apr-Jun;85(4-5):121-30
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6438087
Gene symbol: Casp3
Gene name: caspase 3
Results
Specimen S2B Wt: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: humerus Present Regionally restricted S2B Wt Expressing cells only detected at border to ossification center where hypertrophic chondrocytes undergo apoptosis.
Specimen S2B Gli3delta/delta: embryonic day 15.5; Gli3tm1.2Zllr/Gli3tm1.2Zllr (more )
Structure Level Pattern Image Note
TS23: humerus Weak Regionally restricted S2B Gli3delta/delta Zone of expressing cells was reduced compared with wildtype.
Specimen S2B Vlkdelta/delta: embryonic day 15.5; Pkdcctm1.2Azun/Pkdcctm1.2Azun (more )
Structure Level Pattern Image Note
TS23: humerus Absent S2B Vlkdelta/delta Authors report apoptotic zone was absent. No additional regions were detected.
Specimen S2B Vlkdelta/delta Gli3delta/delta: embryonic day 15.5; Gli3tm1.2Zllr/Gli3tm1.2Zllr, Pkdcctm1.2Azun/Pkdcctm1.2Azun (more )
Structure Level Pattern Image Note
TS23: humerus Absent S2B Vlkdelta/delta Gli3delta/delta Authors report apoptotic zone was absent. No additional regions were detected.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/24/2026
MGI 6.24 		The Jackson Laboratory