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Gene Expression Data
Assay Details
Assay
Reference: J:230169 Isaac J, et al., DLX3 regulates bone mass by targeting genes supporting osteoblast differentiation and mineral homeostasis in vivo. Cell Death Differ. 2014 Sep;21(9):1365-76
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6437489
Gene symbol: Dlx3
Gene name: distal-less homeobox 3
Reporter: lacZ
Direct Detection
Results
Specimen 1Aa: embryonic day 14.5; Dlx3tm2Mso/Dlx3+ (more )
Structure Level Pattern Image Note
TS22: skeleton Strong Regionally restricted 1Aa Expression is in osteoprogenitor cells, bone-forming osteoblasts and matrix-embedded osteocytes in endochondral developing bones.

Specimen 1Ab: embryonic day 14.5; Dlx3tm2Mso/Dlx3+ (more )
Structure Level Pattern Image Note
TS22: forearm mesenchyme Strong Regionally restricted 1Ab Expression is in osteoprogenitor cells, bone-forming osteoblasts and matrix-embedded osteocytes in endochondral developing bones.
TS22: forearm skin Present 1Ab

Specimen 1Ac: embryonic day 14.5; Dlx3tm2Mso/Dlx3+ (more )
Structure Level Pattern Image Note
TS22: radius cartilage condensation Strong Regionally restricted 1Ac Expression is in osteoprogenitor cells, bone-forming osteoblasts and matrix-embedded osteocytes in endochondral developing bones.
TS22: forearm skin Present 1Ac

Specimen 1Ba: embryonic day 16.5; Dlx3tm2Mso/Dlx3+ (more )
Structure Level Pattern Image Note
TS24: humerus Strong Regionally restricted 1Ba , 1Ba1 Expression is in osteoprogenitor cells, bone-forming osteoblasts and matrix-embedded osteocytes in endochondral developing bones.

Specimen 1Ca: postnatal day 1.5; Dlx3tm2Mso/Dlx3+ (more )
Structure Level Pattern Image Note
TS27: chondrocranium Strong Regionally restricted 1Ca Expression is in osteoprogenitor cells, bone-forming osteoblasts and matrix-embedded osteocytes in endochondral developing bones.

Specimen 1Cb: postnatal day 1.5; Dlx3tm2Mso/Dlx3+ (more )
Structure Level Pattern Image Note
TS27: rib Strong Regionally restricted 1Cb Expression is in osteoprogenitor cells, bone-forming osteoblasts and matrix-embedded osteocytes in endochondral developing bones.

Specimen 1Cc: postnatal day 1.5; Dlx3tm2Mso/Dlx3+ (more )
Structure Level Pattern Image Note
TS27: hand bone Strong Regionally restricted 1Cc Expression is in osteoprogenitor cells, bone-forming osteoblasts and matrix-embedded osteocytes in endochondral developing bones.

Specimen 1Cd: postnatal day 1.5; Dlx3tm2Mso/Dlx3+ (more )
Structure Level Pattern Image Note
TS27: tibia Strong Regionally restricted 1Cd Expression is in osteoprogenitor cells, bone-forming osteoblasts and matrix-embedded osteocytes in endochondral developing bones.

Specimen 1Ce: postnatal day 1.5; Dlx3tm2Mso/Dlx3+ (more )
Structure Level Pattern Image Note
TS27: tibia Strong Regionally restricted 1C2 , 1Ce , 1C1 Expression is in osteoprogenitor cells, bone-forming osteoblasts and matrix-embedded osteocytes in endochondral developing bones.

Specimen 1Cf: postnatal day 1.5; Dlx3tm2Mso/Dlx3+ (more )
Structure Level Pattern Image Note
TS27: tibia Strong Regionally restricted 1Cf Expression is in osteoprogenitor cells, bone-forming osteoblasts and matrix-embedded osteocytes in endochondral developing bones.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory