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Gene Expression Data
Assay Details
Assay
Reference: J:287264 Hael CE, et al., The transcriptional regulator PRDM12 is critical for Pomc expression in the mouse hypothalamus and controlling food intake, adiposity, and body weight. Mol Metab. 2020 Apr;34:43-53
Assay type: RT-PCR
MGI Accession ID: MGI:6437118
Gene symbol: Pomc
Gene name: pro-opiomelanocortin-alpha
Probe: Pomc-pC, Pomc-pD
Probe preparation: labelled with SYBR green
Assay notes: Quantitative RT-PCR was used to obtain these results. These data were discussed by not shown.
Results
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex Note
Control E11.5 TS19: diencephalon Present Not Specified; total RNA involves: C57BL/6 Prdm12tm2c(EUCOMM)Hmgu/Prdm12tm2c(EUCOMM)HmguNot Specified hypothalamus
KO E11.5 TS19: diencephalon Present (a) Not Specified; total RNA involves: C57BL/6 Prdm12tm2c(EUCOMM)Hmgu/Prdm12tm2c(EUCOMM)Hmgu, Isl1tm1(cre)Sev/Isl1+Not Specified Conditional mutant. hypothalamus
Notes:
(a) Expression levels are 14% of those found in wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/09/2025
MGI 6.24 		The Jackson Laboratory