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Gene Expression Data
Assay Details
Assay
Reference: J:102348 Nery S, et al., Dlx2 progenitor migration in wild type and Nkx2.1 mutant telencephalon. Cereb Cortex. 2003 Sep;13(9):895-903
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6436361
Gene symbol: Dlx2
Gene name: distal-less homeobox 2
Reporter: lacZ
Direct Detection
Results
Specimen 1B: embryonic day 12.5; Dlx2tm1Fsh/Dlx2+ (more )
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 1B Expression is in the ventral telencephalon.
TS20: caudal ganglionic eminence Present 1B
TS20: lateral ganglionic eminence Present 1B
TS20: medial ganglionic eminence Present 1B
TS20: cerebral cortex Absent 1B
Specimen 1C: embryonic day 12.5; Dlx2tm1Fsh/Dlx2+ (more )
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 1C Expression is in the ventral telencephalon.
TS20: caudal ganglionic eminence Present 1C
TS20: lateral ganglionic eminence Present 1C
TS20: medial ganglionic eminence Present 1C
TS20: cerebral cortex Absent 1C
Specimen 1D: embryonic day 12.5; Dlx2tm1Fsh/Dlx2+ (more )
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 1D Expression is in the ventral telencephalon.
TS20: caudal ganglionic eminence Present 1D
TS20: lateral ganglionic eminence Present 1D
TS20: medial ganglionic eminence Present 1D
TS20: cerebral cortex Absent 1D
Specimen 1E: embryonic day 14.5; Dlx2tm1Fsh/Dlx2+ (more )
Structure Level Pattern Image Note
TS22: medial ganglionic eminence Present 1E , 1F
TS22: telencephalon subventricular zone Present Regionally restricted 1E , 1F Expression is in streams of cells emanating from the ganglionic eminence into the cortex and toward the ventrolateral telencephalon.
Specimen 1H: embryonic day 14.5; Dlx2tm1Fsh/Dlx2+ (more )
Structure Level Pattern Image Note
TS22: caudal ganglionic eminence Present 1G , 1H
TS22: telencephalon subventricular zone Present Regionally restricted 1H , 1G Expression is in streams of cells emanating from the ganglionic eminence into the cortex and toward the ventrolateral telencephalon.
Specimen 1I: embryonic day 16.5; Dlx2tm1Fsh/Dlx2+ (more )
Structure Level Pattern Image Note
TS24: cerebral cortex marginal layer Present 1I , 1J
TS24: cerebral cortex subventricular zone Present 1I , 1J
TS24: telencephalon Present Regionally restricted 1I Expression is in migrating cells along the lateral migratory stream to the ventro-lateral telencephalon.
TS24: cortical plate Present Scattered 1I , 1J
Specimen 1L: embryonic day 16.5; Dlx2tm1Fsh/Dlx2+ (more )
Structure Level Pattern Image Note
TS24: cerebral cortex marginal layer Present 1L , 1K
TS24: cerebral cortex subventricular zone Present 1L , 1K
TS24: cortical plate Present Scattered 1K , 1L
Specimen 1M: postnatal day 3; Dlx2tm1Fsh/Dlx2+ (more )
Structure Level Pattern Image Note
TS27: cerebral cortex subventricular zone Strong 1M
TS27: main olfactory bulb Strong 1M
TS27: cerebral cortex Present Regionally restricted 1M Expression is weak in the mantle layer.
Specimen 1N: postnatal day 3; Dlx2tm1Fsh/Dlx2+ (more )
Structure Level Pattern Image Note
TS27: cerebral cortex marginal zone Present 1N
TS27: cerebral cortex subventricular zone Present 1N
TS27: cerebral hemisphere white matter Present 1N
TS27: cortical plate Present 1N
TS27: telencephalon subventricular zone Strong Regionally restricted 1N Expression is ventral.
Specimen 1O: postnatal day 3; Dlx2tm1Fsh/Dlx2+ (more )
Structure Level Pattern Image Note
TS27: cerebral cortex marginal zone Present 1O
TS27: cerebral hemisphere white matter Present 1O
TS27: cortical plate Present 1O
Specimen 1P: postnatal day 3; Dlx2tm1Fsh/Dlx2+ (more )
Structure Level Pattern Image Note
TS27: hippocampus CA1 Weak 1P
Specimen 1Q: postnatal day 7; Dlx2tm1Fsh/Dlx2+ (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present Regionally restricted 1Q Expression is in the cortical plate.
TS28: cerebral cortex marginal zone Absent 1Q
Specimen 1R: postnatal day 10; Dlx2tm1Fsh/Dlx2+ (more )
Structure Level Pattern Image Note
TS28: cerebral cortex subventricular zone Present 1R
TS28: cerebral hemisphere white matter Present 1R
TS28: rostral migratory stream Present 1R
Specimen 1S: postnatal month 5; Dlx2tm1Fsh/Dlx2+ (more )
Structure Level Pattern Image Note
TS28: cerebral cortex subventricular zone Present 1S
TS28: cerebral hemisphere white matter Present 1S
TS28: rostral migratory stream Present 1S
Specimen 1T: postnatal month 5; Dlx2tm1Fsh/Dlx2+ (more )
Structure Level Pattern Image Note
TS28: cerebral cortex subventricular zone Present 1T
TS28: cerebral hemisphere white matter Present 1T
TS28: rostral migratory stream Present 1T
Specimen 1U: postnatal month 5; Dlx2tm1Fsh/Dlx2+ (more )
Structure Level Pattern Image Note
TS28: cerebral cortex subventricular zone Present 1U
TS28: cerebral hemisphere white matter Present 1U
TS28: rostral migratory stream Present 1U
TS28: hippocampus CA1 Weak 1U
Specimen 5A: embryonic day 13.5; Dlx2tm1Fsh/Dlx2+ (more )
Structure Level Pattern Image Note
TS21: ganglionic eminence Present 5A
TS21: cerebral cortex Present Regionally restricted 5A Expression is in a stream of cells that migrates from the ventral telencephalon to the cortex.
TS21: telencephalon Present Regionally restricted 5A Expression is in a stream of cells that migrates from the ventral telencephalon to the cortex.
Specimen 5B: embryonic day 13.5; Dlx2tm1Fsh/Dlx2+ (more )
Structure Level Pattern Image Note
TS21: ganglionic eminence Present 5B
TS21: cerebral cortex Present Regionally restricted 5B Expression is in a stream of cells that migrates from the ventral telencephalon to the cortex.
TS21: telencephalon Present Regionally restricted 5B Expression is in a stream of cells that migrates from the ventral telencephalon to the cortex.
Specimen 5C: embryonic day 13.5; Dlx2tm1Fsh/Dlx2+, Nkx2-1tm1Shk/Nkx2-1tm1Shk (more )
Structure Level Pattern Image Note
TS21: ganglionic eminence Present 5C
TS21: cerebral cortex Absent 5C
Specimen 5D: embryonic day 13.5; Dlx2tm1Fsh/Dlx2+, Nkx2-1tm1Shk/Nkx2-1tm1Shk (more )
Structure Level Pattern Image Note
TS21: ganglionic eminence Present 5D
TS21: cerebral cortex Absent 5D
Specimen 5E: embryonic day 15.5; Dlx2tm1Fsh/Dlx2+ (more )
Structure Level Pattern Image Note
TS23: ganglionic eminence Present 5E
TS23: cerebral cortex Present Regionally restricted 5E Expression is in a stream of cells.
Specimen 5F: embryonic day 15.5; Dlx2tm1Fsh/Dlx2+ (more )
Structure Level Pattern Image Note
TS23: ganglionic eminence Present 5F
TS23: cerebral cortex Present Regionally restricted 5F Expression is in a stream of cells.
Specimen 5G: embryonic day 15.5; Dlx2tm1Fsh/Dlx2+, Nkx2-1tm1Shk/Nkx2-1tm1Shk (more )
Structure Level Pattern Image Note
TS23: cerebral cortex Weak Regionally restricted 5G Expression is in a stream of cells.
Specimen 5H: embryonic day 15.5; Dlx2tm1Fsh/Dlx2+, Nkx2-1tm1Shk/Nkx2-1tm1Shk (more )
Structure Level Pattern Image Note
TS23: cerebral cortex Weak Regionally restricted 5H Expression is in a stream of cells.
Specimen 5I: embryonic day 18.5; Dlx2tm1Fsh/Dlx2+ (more )
Structure Level Pattern Image Note
TS26: cerebral cortex subventricular zone Present 5I
TS26: cortical plate Present 5I
Specimen 5J: embryonic day 18.5; Dlx2tm1Fsh/Dlx2+ (more )
Structure Level Pattern Image Note
TS26: cerebral cortex subventricular zone Present 5J
TS26: cortical plate Present 5J
Specimen 5K: embryonic day 18.5; Dlx2tm1Fsh/Dlx2+, Nkx2-1tm1Shk/Nkx2-1tm1Shk (more )
Structure Level Pattern Image Note
TS26: cerebral cortex subventricular zone Weak 5K
TS26: cortical plate Weak 5K
Specimen 5L: embryonic day 18.5; Dlx2tm1Fsh/Dlx2+, Nkx2-1tm1Shk/Nkx2-1tm1Shk (more )
Structure Level Pattern Image Note
TS26: cerebral cortex subventricular zone Weak 5L
TS26: cortical plate Weak 5L
Specimen not shown E13.5: embryonic day 13.5; Dlx2tm1Fsh/Dlx2+ (more )
Structure Level Pattern Image Note
TS21: telencephalon Present Regionally restricted Expression is in streams of cells emanating from the ganglionic eminence into the cortex and toward the ventrolateral telencephalon.
TS21: ganglionic eminence Present
Specimen not shown E18.5: embryonic day 18.5; Dlx2tm1Fsh/Dlx2+ (more )
Structure Level Pattern Image Note
TS26: cerebral cortex marginal zone Present
TS26: cerebral hemisphere white matter Present
TS26: cortical plate Present
Specimen not shown P7: postnatal day 7; Dlx2tm1Fsh/Dlx2+ (more )
Structure Level Pattern Image Note
TS28: cerebral hemisphere white matter Present
TS28: telencephalon subventricular zone Present
TS28: ganglionic eminence Weak
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory