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Gene Expression Data
Assay Details
Assay
Reference: J:81783 Lu M, et al., Abnormal development of the hippocampal dentate gyrus in mice lacking the CXCR4 chemokine receptor. Proc Natl Acad Sci U S A. 2002 May 14;99(10):7090-5
Assay type: RNA in situ
MGI Accession ID: MGI:6435715
Gene symbol: Prox1
Gene name: prospero homeobox 1
Probe: Prox1 probe6
Probe preparation: Antisense RNA
Results
Specimen 5A: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: dentate gyrus Present 5A

Specimen 5B: embryonic day 18.5; Cxcr4tm1Yzo/Cxcr4tm1Yzo (more )
Structure Level Pattern Image Note
TS26: dentate gyrus Present 5B
TS26: hippocampal formation Present Regionally restricted 5B Expression is in the migratory stream of dividing cells running along the ventral surface of the hippocampus into the dentate gyrus.

Specimen 5C: embryonic day 18.5 (more )
Note: Double labeled with BrdU (orange).
Structure Level Pattern Image Note
TS26: dentate gyrus Present 5C

Specimen 5D: embryonic day 18.5; Cxcr4tm1Yzo/Cxcr4tm1Yzo (more )
Note: Double labeled with BrdU (orange).
Structure Level Pattern Image Note
TS26: dentate gyrus Present 5D
TS26: hippocampal formation Present Regionally restricted 5E , 5D Expression is in the migratory stream running along the ventral surface of the hippocampus into the dentate gyrus.

Specimen not shown E16.5 WT: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: dentate gyrus primordium Present

Specimen not shown E16.5 -/-: embryonic day 16.5; Cxcr4tm1Yzo/Cxcr4tm1Yzo (more )
Structure Level Pattern Image Note
TS24: dentate gyrus primordium Present
TS24: hippocampal formation Present Regionally restricted Expression is in the migratory stream running along the ventral surface of the hippocampus into the dentate gyrus.

Specimen not shown E17.5 ET: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: dentate gyrus Present

Specimen not shown E17.5 -/-: embryonic day 17.5; Cxcr4tm1Yzo/Cxcr4tm1Yzo (more )
Structure Level Pattern Image Note
TS25: dentate gyrus Present
TS25: hippocampal formation Present Regionally restricted Expression is in the migratory stream running along the ventral surface of the hippocampus into the dentate gyrus.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory