Noto RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:153634 Ukita K, et al., Wnt signaling maintains the notochord fate for progenitor cells and supports the posterior extension of the notochord. Mech Dev. 2009 Oct;126(10):791-803
Assay type:	RNA in situ
MGI Accession ID:	MGI:6434543
Gene symbol:	Noto
Gene name:	notochord homeobox

Probe:	Not cDNA2
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

7A ©

Specimen 7A: embryonic day 9.5 (more

)

Structure	Level	Pattern	Image	Note
TS15: notochord	Present	Regionally restricted	7A	Expression in posterior end of notochord.

7B ©

Specimen 7B: embryonic day 9.5; Ctnnb1^tm2Kem/Ctnnb1^tm2Kem, Tg(Noto-cre)#Knd/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS15: notochord	Trace		7B	Expression dramatically reduced in mutants.

7C ©

Specimen 7C: embryonic day 9.5 (more

)

Structure	Level	Pattern	Image	Note
TS15: notochord	Present		7C

7D ©

Specimen 7D: embryonic day 9.5; Ctnnb1^tm2Kem/Ctnnb1^tm2Kem, Tg(Noto-cre)#Knd/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS15: notochord	Trace		7D	Authors report notochord-like tissue morphologically identifiable.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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