Tg(RBP3-ELOVL4*)M69-123Mrl
Transgene Detail
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Symbol: |
Tg(RBP3-ELOVL4*)M69-123Mrl |
Name: |
transgene insertion M69-123, Merck Research Laboratory |
MGI ID: |
MGI:6434494 |
Transgene: |
Tg(RBP3-ELOVL4*)M69-123Mrl Location: unknown
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Alliance: |
Tg(RBP3-ELOVL4*)M69-123Mrl page
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Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(RBP3-ELOVL4*)M69-123Mrl expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
ELOVL4 (6785) |
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ELOVL4 cDNA harbors the AACTT deletion resulting in progressive photoreceptor degeneration |
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Mutation details: A plasmid containing the human RBP3 promoter, a rabbit beta-globin intron and the human mutant ELOVL4 cDNA harboring the AACTT deletion resulting in progressive photoreceptor degeneration was engineered. Line M69-123 has 1 transgenic copy integrated and shows lowest expression level in ONL.
(J:147112)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:147112 Taconic, Information obtained from Taconic website. MGI Direct Data Submission. 2006-2017; |
All: |
1 reference(s) |
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