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Gene Expression Data
Assay Details
Assay
Reference: J:245773 Paikari A, et al., The eutheria-specific miR-290 cluster modulates placental growth and maternal-fetal transport. Development. 2017 Oct 15;144(20):3731-3743
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6434460
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Antibody: anti-Ki-67 (SP6; MA5-14520, RM-9106)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 4C Wt: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: labyrinthine zone Present 4C Wt

Specimen 4C KO: embryonic day 12.5; Mirc5tm1Jae/Mirc5tm1Jae (more )
Structure Level Pattern Image Note
TS20: labyrinthine zone Present 4C KO There was a small but reproducible reduction in the number of immunopositive cells in the mutant.

Specimen 4E Wt: embryonic day 12.5 (more )
Note: Double labeled: green - Mki67; red - BrdU.
Structure Level Pattern Image Note
TS20: labyrinthine zone Present 4E Wt

Specimen 4E KO: embryonic day 12.5; Mirc5tm1Jae/Mirc5tm1Jae (more )
Note: Double labeled: green - Mki67; red - BrdU.
Structure Level Pattern Image Note
TS20: labyrinthine zone Present 4E KO There was a small but reproducible reduction in the number of immunopositive cells in the mutant. The BrdU/Mki67 ratio remained constant.

Specimen not shown Wt: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: labyrinthine zone Present

Specimen not shown KO: embryonic day 10.5; Mirc5tm1Jae/Mirc5tm1Jae (more )
Structure Level Pattern Image Note
TS17: labyrinthine zone Present There was a small but reproducible reduction in the number of immunopositive cells in the mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory