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Gene Expression Data
Assay Details
Assay
Reference: J:156737 Zhao L, et al., Sonic hedgehog is involved in formation of the ventral optic cup by limiting Bmp4 expression to the dorsal domain. Mech Dev. 2010 January - February;127(1-2):62-72
Assay type: RNA in situ
MGI Accession ID: MGI:6434453
Gene symbol: Bmp4
Gene name: bone morphogenetic protein 4
Probe: Bmp4 probe89
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 6A: embryonic day 9.25; Smotm2Amc/Smo+ (more )
Note: 18 somites
Structure Level Pattern Image Note
TS14: optic vesicle Weak 6A
Specimen 6B: embryonic day 9.25; Smotm2Amc/Smo+, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 18 somites
Structure Level Pattern Image Note
TS14: optic vesicle Weak 6B
Specimen 6C: embryonic day 9.25; Smotm1Amc/Smotm2Amc, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 18 somites
Structure Level Pattern Image Note
TS14: optic vesicle Present 6C Slightly increased expression in optic vesicle compared to controls.
Specimen 6D: embryonic day 9.5; Smotm2Amc/Smo+ (more )
Note: 21 somites
Structure Level Pattern Image Note
TS15: optic vesicle Weak 6D
Specimen 6E: embryonic day 9.5; Smotm2Amc/Smo+, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 21 somites
Structure Level Pattern Image Note
TS15: optic vesicle Weak 6E
Specimen 6F: embryonic day 9.5; Smotm1Amc/Smotm2Amc, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 21 somites
Structure Level Pattern Image Note
TS15: optic vesicle Very strong 6F Expression in optic vescle greatly increased.
Specimen 6D': embryonic day 9.5; Smotm2Amc/Smo+ (more )
Note: 21 somites
Structure Level Pattern Image Note
TS15: optic vesicle Weak 6D'
Specimen 6E': embryonic day 9.5; Smotm2Amc/Smo+, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 21 somites
Structure Level Pattern Image Note
TS15: optic vesicle Weak 6E'
Specimen 6F': embryonic day 9.5; Smotm1Amc/Smotm2Amc, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 21 somites
Structure Level Pattern Image Note
TS15: optic vesicle Strong 6F' Incrreased expression in optic vesicle.
Specimen 6G: embryonic day 10.0; Smotm2Amc/Smo+ (more )
Note: 27 somites
Structure Level Pattern Image Note
TS15: optic cup Present Regionally restricted 6G Expression confined to dorsal optic cup.
Specimen 6H: embryonic day 10.0; Smotm2Amc/Smo+, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 27 somites
Structure Level Pattern Image Note
TS15: optic cup Present Regionally restricted 6H Expression confined to dorsal optic cup.
Specimen 6I: embryonic day 10.0; Smotm1Amc/Smotm2Amc, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 27 somites
Structure Level Pattern Image Note
TS15: optic cup Present Regionally restricted 6I Expression in both dorsal and ventral optic cup.
Specimen 6G': embryonic day 10.0; Smotm2Amc/Smo+ (more )
Note: 27 somites
Structure Level Pattern Image Note
TS16: optic cup Present Regionally restricted 6G' Expression confined to dorsal optic cup.
Specimen 6H': embryonic day 10.0; Smotm2Amc/Smo+, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 27 somites
Structure Level Pattern Image Note
TS15: optic cup Present Regionally restricted 6H' Expression confined to dorsal optic cup.
Specimen 6I': embryonic day 10.0; Smotm1Amc/Smotm2Amc, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 27 somites
Structure Level Pattern Image Note
TS15: optic cup Present Regionally restricted 6I' Expression in both dorsal and ventral optic cup.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
MGI 6.24 		The Jackson Laboratory