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Gene Expression Data
Assay Details
Assay
Reference: J:156737 Zhao L, et al., Sonic hedgehog is involved in formation of the ventral optic cup by limiting Bmp4 expression to the dorsal domain. Mech Dev. 2010 January - February;127(1-2):62-72
Assay type: RNA in situ
MGI Accession ID: MGI:6434452
Gene symbol: Vax2
Gene name: ventral anterior homeobox 2
Probe: Vax2 probe6
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 5J: embryonic day 9.5; Smotm2Amc/Smo+ (more )
Note: 22 somites
Structure Level Pattern Image Note
TS15: optic cup Present 5J
Specimen 5K: embryonic day 9.5; Smotm2Amc/Smo+, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 22 somites
Structure Level Pattern Image Note
TS15: optic cup Present 5K
Specimen 5L: embryonic day 9.5; Smotm1Amc/Smotm2Amc, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 22 somites
Structure Level Pattern Image Note
TS15: optic cup Present 5L Expression patterns in optic cup not obviously different in all genotypes.
Specimen 5M: embryonic day 9.75; Smotm2Amc/Smo+ (more )
Note: 24 somites
Structure Level Pattern Image Note
TS15: optic cup Present 5M
Specimen 5N: embryonic day 9.75; Smotm2Amc/Smo+, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 24 somites
Structure Level Pattern Image Note
TS15: optic cup Present 5N
Specimen 5O: embryonic day 9.75; Smotm1Amc/Smotm2Amc, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 24 somites
Structure Level Pattern Image Note
TS15: optic cup Present Regionally restricted 5O No expression in dorsal optic cup.
Specimen 5P: embryonic day 10.75; Smotm2Amc/Smo+ (more )
Note: 38 somites
Structure Level Pattern Image Note
TS17: optic cup Present Regionally restricted 5P Expression in ventral optic cup.
Specimen 5Q: embryonic day 10.75; Smotm2Amc/Smo+, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 38 somites
Structure Level Pattern Image Note
TS17: optic cup Present Regionally restricted 5Q Expression in ventral optic cup.
Specimen 5R: embryonic day 10.75; Smotm1Amc/Smotm2Amc, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 38 somites
Structure Level Pattern Image Note
TS17: optic cup Absent 5R Expression in ventral optic cup completely disappeared.
Specimen 5J': embryonic day 9.5; Smotm2Amc/Smo+ (more )
Note: 22 somites
Structure Level Pattern Image Note
TS15: optic cup Present 5J'
Specimen 5K': embryonic day 9.5; Smotm2Amc/Smo+, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 22 somites
Structure Level Pattern Image Note
TS15: optic cup Present 5K'
Specimen 5L': embryonic day 9.5; Smotm1Amc/Smotm2Amc, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 22 somites
Structure Level Pattern Image Note
TS15: optic cup Present 5L' Expression patterns in optic cup not obviously different in all genotypes.
Specimen 5M': embryonic day 9.75; Smotm2Amc/Smo+ (more )
Note: 24 somites
Structure Level Pattern Image Note
TS15: optic cup Present 5M'
Specimen 5N': embryonic day 9.75; Smotm2Amc/Smo+, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 24 somites
Structure Level Pattern Image Note
TS15: optic cup Present 5N'
Specimen 5O': embryonic day 9.75; Smotm1Amc/Smotm2Amc, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 24 somites
Structure Level Pattern Image Note
TS15: optic cup Present Regionally restricted 5O' No expression in dorsal optic cup.
Specimen 5P': embryonic day 10.75; Smotm2Amc/Smo+ (more )
Note: 38 somites
Structure Level Pattern Image Note
TS17: optic cup Present Regionally restricted 5P' Expression in ventral optic cup.
Specimen 5Q': embryonic day 10.75; Smotm2Amc/Smo+, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 38 somites
Structure Level Pattern Image Note
TS17: optic cup Present Regionally restricted 5Q' Expression in ventral optic cup.
Specimen 5R': embryonic day 10.75; Smotm1Amc/Smotm2Amc, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 38 somites
Structure Level Pattern Image Note
TS17: optic cup Absent 5R' Expression in ventral optic cup completely disappeared.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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