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Gene Expression Data
Assay Details
Assay
Reference: J:156737 Zhao L, et al., Sonic hedgehog is involved in formation of the ventral optic cup by limiting Bmp4 expression to the dorsal domain. Mech Dev. 2010 January - February;127(1-2):62-72
Assay type: RNA in situ
MGI Accession ID: MGI:6434451
Gene symbol: Vax1
Gene name: ventral anterior homeobox 1
Probe: Vax1 probe3
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 5A: embryonic day 9.5; Smotm2Amc/Smo+ (more )
Note: 20 somites
Structure Level Pattern Image Note
TS14: optic vesicle Present 5A
Specimen 5B: embryonic day 9.5; Smotm2Amc/Smo+, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 20 somites
Structure Level Pattern Image Note
TS14: optic vesicle Present 5B
Specimen 5C: embryonic day 9.5; Smotm1Amc/Smotm2Amc, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 20 somites
Structure Level Pattern Image Note
TS14: optic vesicle Present 5C Expression not obvioiusly different from that of controls.
Specimen 5D: embryonic day 9.75; Smotm2Amc/Smo+ (more )
Note: 24 somites
Structure Level Pattern Image Note
TS15: optic cup Present 5D
Specimen 5E: embryonic day 9.75; Smotm2Amc/Smo+, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 24 somites
Structure Level Pattern Image Note
TS15: optic cup Present 5E
Specimen 5F: embryonic day 9.75; Smotm1Amc/Smotm2Amc, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 24 somites
Structure Level Pattern Image Note
TS15: optic cup Present Regionally restricted 5F No expression in dorsal optic cup.
Specimen 5G: embryonic day 10.0; Smotm2Amc/Smo+ (more )
Note: 30 somites
Structure Level Pattern Image Note
TS16: optic cup Present Regionally restricted 5G Expression in ventral optic cup.
Specimen 5H: embryonic day 10.0; Smotm2Amc/Smo+, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 30 somites
Structure Level Pattern Image Note
TS16: optic cup Present Regionally restricted 5H Expression in ventral optic cup.
Specimen 5I: embryonic day 10.0; Smotm1Amc/Smotm2Amc, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 30 somites
Structure Level Pattern Image Note
TS16: optic cup Weak Regionally restricted 5I Expression downregulated in ventral optic cup.
Specimen 5A': embryonic day 9.5; Smotm2Amc/Smo+ (more )
Note: 20 somites
Structure Level Pattern Image Note
TS14: optic vesicle Present 5A'
Specimen 5B': embryonic day 9.5; Smotm2Amc/Smo+, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 20 somites
Structure Level Pattern Image Note
TS14: optic vesicle Present 5B'
Specimen 5C': embryonic day 9.5; Smotm1Amc/Smotm2Amc, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 20 somites
Structure Level Pattern Image Note
TS14: optic vesicle Present 5C' Expression not obvioiusly different from that of controls.
Specimen 5D': embryonic day 9.75; Smotm2Amc/Smo+ (more )
Note: 24 somites
Structure Level Pattern Image Note
TS15: optic cup Present 5D'
Specimen 5E': embryonic day 9.75; Smotm2Amc/Smo+, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 24 somites
Structure Level Pattern Image Note
TS15: optic cup Present 5E'
Specimen 5F': embryonic day 9.75; Smotm1Amc/Smotm2Amc, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 24 somites
Structure Level Pattern Image Note
TS15: optic cup Present Regionally restricted 5F' No expression in dorsal optic cup.
Specimen 5G': embryonic day 10.0; Smotm2Amc/Smo+ (more )
Note: 30 somites
Structure Level Pattern Image Note
TS16: optic cup Present Regionally restricted 5G' Expression in ventral optic cup.
Specimen 5H': embryonic day 10.0; Smotm2Amc/Smo+, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 30 somites
Structure Level Pattern Image Note
TS16: optic cup Present Regionally restricted 5H' Expression in ventral optic cup.
Specimen 5I': embryonic day 10.0; Smotm1Amc/Smotm2Amc, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 30 somites
Structure Level Pattern Image Note
TS16: optic cup Weak Regionally restricted 5I' Expression downregulated in ventral optic cup.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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