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Gene Expression Data
Assay Details
Assay
Reference: J:156737 Zhao L, et al., Sonic hedgehog is involved in formation of the ventral optic cup by limiting Bmp4 expression to the dorsal domain. Mech Dev. 2010 January - February;127(1-2):62-72
Assay type: RNA in situ
MGI Accession ID: MGI:6434449
Gene symbol: Pax6
Gene name: paired box 6
Probe: Pax6 probe63
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4A: embryonic day 9.75; Smotm2Amc/Smo+ (more )
Note: 27 somites
Structure Level Pattern Image Note
TS15: optic vesicle Present 4A
Specimen 4B: embryonic day 9.75; Smotm2Amc/Smo+, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 27 somites
Structure Level Pattern Image Note
TS15: optic vesicle Present 4B
Specimen 4C: embryonic day 9.75; Smotm1Amc/Smotm2Amc, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 27 somites
Structure Level Pattern Image Note
TS15: optic vesicle Present 4C Authors report normal expression.
Specimen 4D: embryonic day 10.0; Smotm2Amc/Smo+ (more )
Note: 30 somites
Structure Level Pattern Image Note
TS16: optic cup Present Regionally restricted 4D Expression in ventral optic cup.
Specimen 4E: embryonic day 10.0; Smotm2Amc/Smo+, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 30 somites
Structure Level Pattern Image Note
TS16: optic cup Present Regionally restricted 4E Expression in ventral optic cup.
Specimen 4F: embryonic day 10.0; Smotm1Amc/Smotm2Amc, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 30 somites
Structure Level Pattern Image Note
TS16: optic cup Present Regionally restricted 4F Disturbed expression in ventral optic cup.
Specimen 4G: embryonic day 10.5; Smotm2Amc/Smo+ (more )
Note: 35 somites
Structure Level Pattern Image Note
TS17: optic cup Present Regionally restricted 4G Expression in both dorsal and ventral optic cup.
Specimen 4H: embryonic day 10.5; Smotm2Amc/Smo+, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 35 somites
Structure Level Pattern Image Note
TS17: optic cup Present Regionally restricted 4H Expression in both dorsal and ventral optic cup.
Specimen 4I: embryonic day 10.5; Smotm1Amc/Smotm2Amc, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 35 somites
Structure Level Pattern Image Note
TS17: optic cup Present Regionally restricted 4I Expression confined to dorsal optic cup.
TS17: lens pit Present 4I Expression in hypomorphic lens.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory