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Gene Expression Data
Assay Details
Assay
Reference: J:98484 Lickert H, et al., Dissecting Wnt/{beta}-catenin signaling during gastrulation using RNA interference in mouse embryos. Development. 2005 Jun;132(11):2599-609
Assay type: RNA in situ
MGI Accession ID: MGI:6432912
Gene symbol: Ifitm1
Gene name: interferon induced transmembrane protein 1
Probe: IMAGE clone 657273
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3G MS: embryonic day 7.0; Ctnnb1tm2Kem/Ctnnb1tm2.1Kem (more )
Note: Mid-streak stage.
Structure Level Pattern Image Note
TS10: allantois Present 3G MS Expression first detected in region where allantois will form.

Specimen 3G HF: embryonic day 7.5; Ctnnb1tm2Kem/Ctnnb1tm2.1Kem (more )
Note: Headfold stage.
Structure Level Pattern Image Note
TS11: lateral plate mesoderm Strong 3G HF Prominent expression in primitive streak region and in lateral plate mesoderm.
TS11: primitive streak Strong 3G HF Prominent expression in primitive streak region and in lateral plate mesoderm.

Specimen 3G 10 somites: embryonic day 8.5; Ctnnb1tm2Kem/Ctnnb1tm2.1Kem (more )
Note: 10-somite stage.
Structure Level Pattern Image Note
TS13: lateral plate mesoderm Present 3G 10 somites Expression confined to lateral plate mesoderm and paraxial mesoderm.
TS13: paraxial mesenchyme Present 3G 10 somites Expression confined to lateral plate mesoderm and paraxial mesoderm.
TS13: somite Present Regionally restricted 3G 10 somites Expression in first forming somite in tailbud region.

Specimen 4C wt: embryonic day 7.5; Ctnnb1tm2Kem/Ctnnb1tm2.1Kem (more )
Structure Level Pattern Image Note
TS11: primitive streak Present 4C wt

Specimen 4C CKO: embryonic day 7.5; Ctnnb1tm2Kem/Ctnnb1tm2.1Kem, Krt19tm1(cre)Mmt/Krt19+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS11: primitive streak Absent 4C CKO Expression dowregulated in primitive streak of mutant.
TS11: primordial germ cell of base of allantois Weak 4C CKO Weak expression at base of allantois, where primordial germ cells are located.

Specimen 4F wt: embryonic day 7.5; Ctnnb1tm2Kem/Ctnnb1tm2.1Kem (more )
Structure Level Pattern Image Note
TS11: primitive streak Present 4F wt


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory