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Gene Expression Data
Assay Details
Assay
Reference: J:166893 Cote M, et al., Apolipoprotein C-II and lipoprotein lipase show a temporal and geographic correlation with surfactant lipid synthesis in preparation for birth. BMC Dev Biol. 2010;10:111
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6431577
Gene symbol: Apoc2
Gene name: apolipoprotein C2
Antibody: anti-apoC-II (T-12)
Detection system: Secondary antibody
Results
Specimen 1H: embryonic day 15.5 (more )
Note: Pseudoglandular stage of lung morphogenesis.
Structure Level Pattern Image Note
TS23: lung epithelium Present Diffuse 1H Expression is in the cytoplasm.
Specimen 1I: embryonic day 16.5 (more )
Note: Canalicular stage of lung morphogenesis.
Structure Level Pattern Image Note
TS24: lung epithelium Present 1I There is a diffuse positive signal in the cytoplasm of epithelial cells and a few dots looking like secretory granules.
Specimen 1J: embryonic day 16.5 (more )
Note: Canalicular stage of lung morphogenesis.
Structure Level Pattern Image Note
TS24: lung epithelium Present Regionally restricted 1J Expression is in small positive dots and there is no diffuse signal in the epithelium.
Specimen 1K: embryonic day 17.5 (more )
Note: Late canalicular stage of lung morphogenesis.
Structure Level Pattern Image Note
TS25: lung epithelium Present Regionally restricted 1K Expression is in the most distal epithelium before apparition of the lumina in structures looking like secretory granules mainly localized near the basal membrane close to the mesenchyme.
Specimen 1L: embryonic day 17.5 (more )
Note: Late canalicular stage of lung morphogenesis.
Structure Level Pattern Image Note
TS25: lung epithelium Present Regionally restricted 1L Expression is in the distal epithelium with lumina.
Specimen 5G: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: lung epithelium Present Regionally restricted 5G Expression is in secretory granules in distal epithelia with no or small lumina and not with large lumina.
Specimen 5H: embryonic day 19.5 (more )
Structure Level Pattern Image Note
TS26: lung epithelium Present 5H Expression is in secretory granules in distal epithelia with no or small lumina and not with large lumina.
Specimen 5I: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: lung epithelium Absent 5I
Specimen 5K: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: lung epithelium Absent 5K
Specimen 5L: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: respiratory bronchiole epithelium Present 5L Expression is near the basal membrane close to the mesenchyme.
Specimen 5M: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: respiratory bronchiole epithelium Present Regionally restricted 5M Expression is in a few secretaory granules near the basal membrane close to the mesenchyme.
Specimen 5O: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: capillary Present 5O Expression was seen in 1/3 of the mice analyzed.
TS28: lung vascular element Present 5O Expression was seen in 1/3 of the mice analyzed.
TS28: lung alveolus Present Regionally restricted 5O in presumable macrophages
Specimen not shown: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: lung alveolus Present Regionally restricted Expression is in the alveolar space in presumable macrophages.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory