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Gene Expression Data
Assay Details
Assay
Reference: J:192194 Tortelote GG, et al., Wnt3 function in the epiblast is required for the maintenance but not the initiation of gastrulation in mice. Dev Biol. 2013 Feb 1;374(1):164-73
Assay type: RNA in situ
MGI Accession ID: MGI:6430587
Gene symbol: Sp5
Gene name: trans-acting transcription factor 5
Probe: Sp5 cDNA3
Probe preparation: labelled with digoxigenin RNA
Results
Specimen 1F: embryonic day 6.5; Wnt3tm2Amc/Wnt3+, Edil3Tg(Sox2-cre)1Amc/Edil3+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS9: embryo ectoderm Present Regionally restricted 1F Expression in posterior epiblast.
Specimen 1F Epi KO: embryonic day 6.5; Wnt3tm1Bhr/Wnt3tm2Amc, Edil3Tg(Sox2-cre)1Amc/Edil3+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS9: embryo ectoderm Absent 1F Epi KO No expression in posterior epiblast.
Specimen 2B: embryonic day 7.5; Wnt3tm2Amc/Wnt3+, Edil3Tg(Sox2-cre)1Amc/Edil3+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS11: embryo ectoderm Present 2B
Specimen 2B Epi KO (left): embryonic day 7.5; Wnt3tm1Bhr/Wnt3tm2Amc, Edil3Tg(Sox2-cre)1Amc/Edil3+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS11: embryo ectoderm Weak 2B Epi KO (left) Authors report diminished expression in epiblast.
Specimen 2B Epi KO (center): embryonic day 7.5; Wnt3tm1Bhr/Wnt3tm2Amc, Edil3Tg(Sox2-cre)1Amc/Edil3+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS11: embryo ectoderm Weak 2B Epi KO (center) Authors report diminished expression in epiblast.
Specimen 2B Epi KO (right): embryonic day 7.5; Wnt3tm1Bhr/Wnt3tm2Amc, Edil3Tg(Sox2-cre)1Amc/Edil3+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS11: embryo ectoderm Weak 2B Epi KO (right) Authors report diminished expression in epiblast.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory