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Gene Expression Data
Assay Details
Assay
Reference: J:190539 Bialecka M, et al., Cdx2 contributes to the expansion of the early primordial germ cell population in the mouse. Dev Biol. 2012 Nov 15;371(2):227-34
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6430491
Gene symbol: Ifitm3
Gene name: interferon induced transmembrane protein 3
Antibody: anti-Fragilis
Assay notes: Pre-somitic stage embryos were dissected as described by Lawson et al. (1999).
Results
Specimen 3A: embryonic day 7.5 (more )
Note: Double labeled: red - Fragilis (Ifitm3); green - Blimp1 (Prdm1 assay MGI:6430489).
Structure Level Pattern Image Note
TS11: primordial germ cell Present 3A
Specimen 3B: embryonic day 7.5; Cdx2tm2Fbe/Cdx2tm2Fbe, Edil3Tg(Sox2-cre)1Amc/Edil3+ (more )
Note: Conditional mutant. Double labeled: red - Fragilis (Ifitm3); green - Blimp1 (Prdm1 assay MGI:6430489).
Structure Level Pattern Image Note
TS11: primordial germ cell Present 3B Authors report reduced numbers of primordial germ cells (PGCs).
Specimen 3C: embryonic day 7.5; Cdx2tm2Fbe/Cdx2tm2Fbe, Edil3Tg(Sox2-cre)1Amc/Edil3+ (more )
Note: Conditional mutant. Double labeled: red - Fragilis (Ifitm3); green - Blimp1 (Prdm1 assay MGI:6430489).
Structure Level Pattern Image Note
TS11: primordial germ cell Present Clusters 3C Some primordial germ cells (PGCs) are strongly clustered.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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