Prdm1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:190539 Bialecka M, et al., Cdx2 contributes to the expansion of the early primordial germ cell population in the mouse. Dev Biol. 2012 Nov 15;371(2):227-34
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6430489
Gene symbol:	Prdm1
Gene name:	PR domain containing 1, with ZNF domain

Antibody:	Blimp-1 antibody
Assay notes:	Pre-somitic stage embryos were dissected as described by Lawson et al. (1999).

Results

3A ©

Specimen 3A: embryonic day 7.5 (more

)
Note: Double labeled: green - Prdm1; red - Ifitm3 (assay MGI:6430491).

Structure	Level	Pattern	Image	Note
TS11: primordial germ cell	Present		3A

3B ©

Specimen 3B: embryonic day 7.5; Cdx2^tm2Fbe/Cdx2^tm2Fbe, Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ (more

)
Note: Conditional mutant. Double labeled: green - Prdm1; red - Ifitm3 (assay MGI:6430491).

Structure	Level	Pattern	Image	Note
TS11: primordial germ cell	Present		3B	Authors report reduced numbers of primordial germ cells (PGCs).

3C ©

Specimen 3C: embryonic day 7.5; Cdx2^tm2Fbe/Cdx2^tm2Fbe, Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ (more

)
Note: Conditional mutant. Double labeled: green - Prdm1; red - Ifitm3 (assay MGI:6430491).

Structure	Level	Pattern	Image	Note
TS11: primordial germ cell	Present	Clusters	3C	Some primordial germ cells (PGCs) are strongly clustered.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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