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Gene Expression Data
Assay Details
Assay
Reference: J:288137 Bilinska K, et al., Expression of the SARS-CoV-2 Entry Proteins, ACE2 and TMPRSS2, in Cells of the Olfactory Epithelium: Identification of Cell Types and Trends with Age. ACS Chem Neurosci. 2020 Jun 3;11(11):1555-1562
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6430272
Gene symbol: Ace2
Gene name: angiotensin converting enzyme 2
Antibody: anti-ACE2 (21115-1-AP)
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 4A: postnatal (more )
Note: Double labeled: red - Ace2; green - Omp (assay MGI:6430291)
Structure Level Pattern Image Note
TS28: olfactory epithelium Present Regionally restricted 4D , 4A Labeling is located just below the luminal surface, between the olfactory receptor knobs and cilia and the layer of olfactory receptor neurons.

Specimen 4E: postnatal (more )
Note: Double labeled: red - Ace2; green - Omp (assay MGI:6430291)
Structure Level Pattern Image Note
TS28: olfactory epithelium Present Regionally restricted 4H , 4E Labeling is seen in the sustentacular cells.

Specimen 4I: postnatal (more )
Note: Double labeled: red - Ace2; green - Omp (assay MGI:6430291)
Structure Level Pattern Image Note
TS28: main olfactory bulb mitral cell layer Present Regionally restricted 4L , 4I Labeling is seen in some mitral neurons.
TS28: main olfactory bulb glomerular layer Absent 4I , 4L
TS28: olfactory nerve Absent 4L , 4I No labeling seen in the olfactory nerve layer.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory