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Gene Expression Data
Assay Details
Assay
Reference: J:288137 Bilinska K, et al., Expression of the SARS-CoV-2 Entry Proteins, ACE2 and TMPRSS2, in Cells of the Olfactory Epithelium: Identification of Cell Types and Trends with Age. ACS Chem Neurosci. 2020 Jun 3;11(11):1555-1562
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6430262
Gene symbol: Ace2
Gene name: angiotensin converting enzyme 2
Antibody: anti-ACE2 (21115-1-AP)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3A: postnatal (more )
Structure Level Pattern Image Note
TS28: olfactory epithelium Present Regionally restricted 3C , 3A A thin layer of labeling is visible at the luminal surface, adjacent to the nasal cavity.
Specimen 3D: postnatal (more )
Structure Level Pattern Image Note
TS28: olfactory epithelium Present Regionally restricted 3F , 3D Expression is seen in the sustentacular cells (especially the cell bodies).
Specimen 3G: postnatal (more )
Structure Level Pattern Image Note
TS28: nasal cavity respiratory epithelium Weak 3G , 3I
Specimen 3J: postnatal (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb mitral cell layer Present Regionally restricted 3J , 3L Expression is seen in some mitral cells, including their proximal dendrites.
TS28: main olfactory bulb glomerular layer Absent 3J , 3L No or very low signal was detected in glomeruli or periglomerular interneurons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory