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Gene Expression Data
Assay Details
Assay
Reference: J:157956 Gordon J, et al., Evidence for an early role for BMP4 signaling in thymus and parathyroid morphogenesis. Dev Biol. 2010 Mar 1;339(1):141-54
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6429911
Gene symbol: Ptprc
Gene name: protein tyrosine phosphatase receptor type C
Antibody: anti-CD45
Detection system: Secondary antibody coupled to Cy5
Results
Specimen 3E: embryonic day 11.5 (more )
Note: Triple labeled: red - CD45 (Ptprc); green - BrdU; blue - pan-keratin.
Structure Level Pattern Image Note
TS19: thymus/parathyroid primordium Present 3E
Specimen 3F: embryonic day 11.5; Bmp4tm1Blh/Bmp4tm4Blh, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant. Triple labeled: red - CD45 (Ptprc); green - BrdU; blue - pan-keratin.
Structure Level Pattern Image Note
TS19: thymus/parathyroid primordium Present 3F
Specimen 4A: embryonic day 11.5 (more )
Note: Double labeled: red - CD45 (Ptprc); blue - pan-keratin.
Structure Level Pattern Image Note
TS19: thymus/parathyroid primordium Present Regionally restricted 4A Expression in lymphocyte progenitor cells around edge of epithelium, and in several cells within primordium.
Specimen 4B: embryonic day 11.5; Bmp4tm1Blh/Bmp4tm4Blh, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant. Double labeled: red - CD45 (Ptprc); blue - pan-keratin.
Structure Level Pattern Image Note
TS19: thymus/parathyroid primordium Weak Regionally restricted 4B Expression in only a few cells at dorsal end.
Specimen 4C: embryonic day 12.5 (more )
Note: Double labeled: red - CD45 (Ptprc); blue - pan-keratin.
Structure Level Pattern Image Note
TS20: thymus primordium Present 4C
Specimen 4D: embryonic day 12.5; Bmp4tm1Blh/Bmp4tm4Blh, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant. Double labeled: red - CD45 (Ptprc); blue - pan-keratin.
Structure Level Pattern Image Note
TS20: thymus primordium Present 4D No obvious difference between mutant and controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory