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Gene Expression Data
Assay Details
Assay
Reference: J:119681 Bates MD, et al., The Hlx homeobox transcription factor is required early in enteric nervous system development. BMC Dev Biol. 2006;6:33
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6416163
Gene symbol: Phox2b
Gene name: paired-like homeobox 2b
Antibody: anti-Phox2b
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 3A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: enteric nervous system Present Scattered 3A
TS17: gut mesenchyme Present Scattered 3A

Specimen 3B: embryonic day 10.5; Hlxtm1Rph/Hlxtm1Rph (more )
Structure Level Pattern Image Note
TS17: enteric nervous system Present Single cells 3B Only a few lightly-stained cells were seen.
TS17: gut mesenchyme Present Single cells 3B Only a few lightly-stained cells were seen.

Specimen 4A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: enteric nervous system Present Regionally restricted 4A Expressed as an incomplete ring in proximal intestinal loops, still scattered more distally.
TS19: intestine mesenchyme Present Regionally restricted 4A Expressed as an incomplete ring in proximal intestinal loops, still scattered more distally.

Specimen 4B: embryonic day 11.5; Hlxtm1Rph/Hlxtm1Rph (more )
Structure Level Pattern Image Note
TS19: enteric nervous system Present Regionally restricted 4B Expressed only in the mesenchyme of the lateral wall of the stomach and not more distally in the gastrointestinal tract.
TS19: stomach mesenchyme Present Regionally restricted 4B Expressed only in the mesenchyme of the lateral wall of the stomach and not more distally in the gastrointestinal tract.
TS19: intestine mesenchyme Absent 4B


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory