Tg(Il4-HBEGF)1Kubo Transgene Detail MGI Mouse (MGI:6407405)

Tg(Il4-HBEGF)1Kubo
Transgene Detail

Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Summary

Symbol:	Tg(Il4-HBEGF)1Kubo
Name:	transgene insertion 1, Masato Kubo
MGI ID:	MGI:6407405
Synonyms:	Mas-TRECK
Transgene:	Tg(Il4-HBEGF)1Kubo Location: unknown
Alliance:	Tg(Il4-HBEGF)1Kubo page

Transgene
origin

Strain of Origin:

C57BL/6

Transgene
description

Transgene Type:

Transgenic (Inserted expressed sequence)

Mutation:

Insertion

Tg(Il4-HBEGF)1Kubo expresses 1 gene

Mutation details: Mice express the human DTR under the control of an IE element in intron 2 of the Il4 gene specifically regulate IL-4 expression in mast cells, leading to mast cell deletion. (J:181174)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

Original:	J:181174 Sawaguchi M, et al., Role of mast cells and basophils in IgE responses and in allergic airway hyperresponsiveness. J Immunol. 2012 Feb 15;188(4):1809-18
All:	20 reference(s)

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