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Gene Expression Data
Assay Details
Assay
Reference: J:123756 Wiener RS, et al., Angiotensin converting enzyme 2 is primarily epithelial and is developmentally regulated in the mouse lung. J Cell Biochem. 2007 Aug 1;101(5):1278-91
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6406779
Gene symbol: Ace2
Gene name: angiotensin converting enzyme 2
Antibody: anti-Ace2 (abcam; ab15348)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 5D: postnatal adult (more )
Structure Level Pattern Image Note
TS28: bronchiole epithelium Present 5D Expression is seen in the Clara cells; it is not seen in the ciliated epithelium.
Specimen 5E: postnatal adult (more )
Structure Level Pattern Image Note
TS28: lung vascular element Present 5E Expression is seen in the vascular endothelium of some medium to large arterioles and venules; it is not seen in alveolar capillaries.
Specimen 5I: postnatal adult (more )
Note: fixative also contained 0.1% glutaraldehyde; antigen retrieval was also performed
Structure Level Pattern Image Note
TS28: venule endothelium Present 5I Expression is seen in the lung.
Specimen 5J: embryonic day 18.5 (more )
Note: fixative also contained 0.1% glutaraldehyde; antigen retrieval was also performed
Structure Level Pattern Image Note
TS26: bronchiole epithelium Present 5J Expression is seen in the non-ciliated epithelium.
Specimen 5K: embryonic day 18.5 (more )
Note: fixative also contained 0.1% glutaraldehyde; antigen retrieval was also performed
Structure Level Pattern Image Note
TS26: lung Present Regionally restricted 5K Expression is seen in the non-ciliated bronchiolar epithelium but is not detected in the distal lung or vasculature.
Specimen 5M: postnatal adult (more )
Structure Level Pattern Image Note
TS28: renal cortex Present 5M Weak staining is observed in the glomeruli.
TS28: renal medulla Absent 5M
Specimen 5O: postnatal adult (more )
Structure Level Pattern Image Note
TS28: renal proximal tubule Present 5O Expression is seen in the proximal tubule brush border.
Specimen 5Q: postnatal adult (more )
Note: fixative also contained 0.1% glutaraldehyde; antigen retrieval was also performed
Structure Level Pattern Image Note
TS28: heart blood vessel Strong 5Q Strong staining in the myocardial capillaries.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory