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Gene Expression Data
Assay Details
Assay
Reference: J:15801 Sarthy V, Collagen IV mRNA expression during development of the mouse retina: an in situ hybridization study. Invest Ophthalmol Vis Sci. 1993 Jan;34(1):145-52
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6405221
Gene symbol: Col4a1
Gene name: collagen, type IV, alpha 1
Antibody: anti-collagen IV
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 1A: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: hyaloid vascular plexus Strong 1A
TS20: lens vesicle Strong Graded 1A Expression is strongest at the cortex and decreases towards the nucleus.
TS20: retina Very strong Regionally restricted 1A Expression is in the inner limiting membrane, and there is staining at the apical side.
TS20: neural retina Weak 1A

Specimen 1B: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: hyaloid vascular plexus Strong 1B
TS20: lens vesicle Strong Regionally restricted 1B Expression is strongest at the cortex and decreases towards the nucleus.
TS20: retina Very strong Regionally restricted 1B Expression is in the inner limiting membrane and there is staining at the apical side.
TS20: neural retina Weak 1B

Specimen 1C: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: hyaloid vascular plexus Present 1C
TS23: lens Present Regionally restricted 1C Expression is strongest at the cortex and decreases towards the nucleus.
TS23: retina Present Regionally restricted 1C Expression is in the inner limiting membrane and extends from the central retina to the periphery.

Specimen 1D: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: choroid layer Present 1D
TS23: pigmented retinal epithelium Present 1D
TS23: retina Present Regionally restricted 1D Expression is in the inner limiting membrane and extends from the central retina to the periphery.

Specimen 1E: embryonic day 20.0 (more )
Structure Level Pattern Image Note
TS26: hyaloid vascular plexus Present 1E
TS26: pigmented retinal epithelium Present 1E
TS26: choroid layer Present Regionally restricted 1E Expression is in Bruch's membrane.
TS26: retina Weak Regionally restricted 1E Expression is in the inner limiting membrane.

Specimen 2A: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: ciliary body Strong 2A
TS27: hyaloid vascular plexus Strong 2A
TS27: lens Strong 2A
TS27: pigmented retinal epithelium Strong 2A
TS27: retina Weak Regionally restricted 2A Expression is in the inner limiting membrane.

Specimen 2B: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: ciliary body Strong 2B
TS27: hyaloid vascular plexus Strong 2B
TS27: lens Strong 2B
TS27: pigmented retinal epithelium Strong 2B
TS27: retina Weak Regionally restricted 2B Expression is in the inner limiting membrane.

Specimen 2C: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: ciliary body Strong 2C
TS28: hyaloid vascular plexus Strong 2C
TS28: lens Strong 2C
TS28: pigmented retinal epithelium Strong 2C
TS28: retina Weak Regionally restricted 2C Expression is in the inner limiting membrane.

Specimen 2D: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: ciliary body Strong 2D
TS28: hyaloid vascular plexus Strong 2D
TS28: lens Strong 2D
TS28: pigmented retinal epithelium Strong 2D
TS28: retina Weak Regionally restricted 2D Expression is in the inner limiting membrane.

Specimen 2E: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: ciliary body Strong 2E
TS27: hyaloid vascular plexus Strong 2E
TS27: lens Strong 2E
TS27: pigmented retinal epithelium Strong 2E
TS27: retina Weak Regionally restricted 2E Expression is in the inner limiting membrane.

Specimen 2F: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: ciliary body Strong 2F
TS28: hyaloid vascular plexus Strong 2F
TS28: lens Strong 2F
TS28: pigmented retinal epithelium Strong 2F

Specimen not shwon: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: retina Present Regionally restricted Expression is in the inner limiting membrane.
TS25: ciliary body Present


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory