About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:155937 Bell CE, et al., SNAI1 and SNAI2 are asymmetrically expressed at the 2-cell stage and become segregated to the TE in the mouse blastocyst. PLoS One. 2009;4(12):e8530
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6404477
Gene symbol: Snai1
Gene name: snail family zinc finger 1
Antibody: anti-SNAI1 (ab17732)
Detection system: Secondary antibody
Results
Specimen 2A: embryonic day 0.5 (more )
Note: Zygote stage embryo. Filamentous actin (red).
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present 2A Expression is in discrete foci in cortical regions throughout the zygote.
Specimen 3A No detection: embryonic day 1.0 (more )
Note: 2-cell stage embryo. Filamentous actin (red).
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Present 3A No detection Proportion of 2-cell stage embryos that had in both cells no detection (6%), one cell asymmetrical and one cell no detection (16%), symmetrical expression and no detection (9%), symmetrical and asymmetrical expression (16%), both cells asymmetrical expression (25%), and both cells symmetrical expression (28%).
Specimen 3A Asym./No detection: embryonic day 1.0 (more )
Note: 2-cell stage embryo. Filamentous actin (red).
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Present 3A Asym./No detection Proportion of 2-cell stage embryos that had in both cells no detection (6%), one cell asymmetrical and one cell no detection (16%), symmetrical expression and no detection (9%), symmetrical and asymmetrical expression (16%), both cells asymmetrical expression (25%), and both cells symmetrical expression (28%).
Specimen 3A Symm./No detection: embryonic day 1.0 (more )
Note: 2-cell stage embryo. Filamentous actin (red).
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Present 3A Symm./No detection Proportion of 2-cell stage embryos that had in both cells no detection (6%), one cell asymmetrical and one cell no detection (16%), symmetrical expression and no detection (9%), symmetrical and asymmetrical expression (16%), both cells asymmetrical expression (25%), and both cells symmetrical expression (28%).
Specimen 3A Symm./Asym.: embryonic day 1.0 (more )
Note: 2-cell stage embryo. Filamentous actin (red).
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Present 3A Symm./Asym. Proportion of 2-cell stage embryos that had in both cells no detection (6%), one cell asymmetrical and one cell no detection (16%), symmetrical expression and no detection (9%), symmetrical and asymmetrical expression (16%), both cells asymmetrical expression (25%), and both cells symmetrical expression (28%).
Specimen 3A Both Asymmetrical: embryonic day 1.0 (more )
Note: 2-cell stage embryo. Filamentous actin (red).
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Present 3A Both Asymmetrical Proportion of 2-cell stage embryos that had in both cells no detection (6%), one cell asymmetrical and one cell no detection (16%), symmetrical expression and no detection (9%), symmetrical and asymmetrical expression (16%), both cells asymmetrical expression (25%), and both cells symmetrical expression (28%).
Specimen 3A Both Symmetrical: embryonic day 1.0 (more )
Note: 2-cell stage embryo. Filamentous actin (red).
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Present 3A Both Symmetrical Proportion of 2-cell stage embryos that had in both cells no detection (6%), one cell asymmetrical and one cell no detection (16%), symmetrical expression and no detection (9%), symmetrical and asymmetrical expression (16%), both cells asymmetrical expression (25%), and both cells symmetrical expression (28%).
Specimen 4A Asym./No detection: embryonic day 2.0 (more )
Note: 4-cell stage embryo. Filamentous actin (red).
Structure Level Pattern Image Note
TS3: 4-cell stage embryo Present 4A Asym./No detection Proportion of 4-cell stage embryos that had asymmetrical and no detection (23%), symmetrical expression and no detection (38%), asymmetrical expression (23%), and symmetrical expression (15%).
Specimen 4A Symm./No detection: embryonic day 2.0 (more )
Note: 4-cell stage embryo. Filamentous actin (red).
Structure Level Pattern Image Note
TS3: 4-cell stage embryo Present 4A Symm./No detection Proportion of 4-cell stage embryos that had asymmetrical and no detection (23%), symmetrical expression and no detection (38%), asymmetrical expression (23%), and symmetrical expression (15%).
Specimen 4A Asymmetrical: embryonic day 2.0 (more )
Note: 4-cell stage embryo. Filamentous actin (red).
Structure Level Pattern Image Note
TS3: 4-cell stage embryo Present 4A Asymmetrical Proportion of 4-cell stage embryos that had asymmetrical and no detection (23%), symmetrical expression and no detection (38%), asymmetrical expression (23%), and symmetrical expression (15%).
Specimen 4A Symmetrical: embryonic day 2.0 (more )
Note: 4-cell stage embryo. Filamentous actin (red).
Structure Level Pattern Image Note
TS3: 4-cell stage embryo Present 4A Symmetrical Proportion of 4-cell stage embryos that had asymmetrical and no detection (23%), symmetrical expression and no detection (38%), asymmetrical expression (23%), and symmetrical expression (15%).
Specimen 5A 8-cell: embryonic day 2.5 (more )
Note: 8-cell stage embryo. Filamentous actin (red).
Structure Level Pattern Image Note
TS3: 8-cell stage embryo Present 5A 8-cell 83% of the blastomeres showed expression.
Specimen 5A Compacted: embryonic day 3.0 (more )
Note: Compacted embryo. Filamentous actin (red).
Structure Level Pattern Image Note
TS4: compacted morula Present 5A Compacted Expression is in the outer cells only and is absent in the inner cells (55% of the blastomeres showed expression).
Specimen 5A Blastocyst: embryonic day 3.5 (more )
Note: Blastocyst stage embryo. Filamentous actin (red).
Structure Level Pattern Image Note
TS4: trophectoderm Present Regionally restricted 5A Blastocyst 40% of the blastomeres showed expression.
TS4: inner cell mass Absent 5A Blastocyst
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory