Gene Expression Data
Assay Details
Assay
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Reference:
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J:188692
Dixit R, et al., Ascl1 participates in Cajal-Retzius cell development in the neocortex. Cereb Cortex. 2011 Nov;21(11):2599-611
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6404058
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Gene symbol:
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Reln
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Gene name:
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reelin
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Probe:
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Reln probe9
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
4C:
embryonic day 12.5
(more )
Note: sagittal section
Specimen
4C:
(close )
Genetic Background:
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involves: 129 * CD-1
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Age:
|
embryonic day 12.5
|
Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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sagittal section
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: cerebral cortex |
Present |
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4C
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Expression is present in Cajal-Retzius cells.
|
Specimen
4C':
embryonic day 12.5
(more )
Note: sagittal section
Specimen
4C':
(close )
Genetic Background:
|
involves: 129 * CD-1
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
sagittal section
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: cortical preplate |
Present |
|
4C'
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Expression is present in Cajal-Retzius cells.
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Specimen
4D:
(close )
Genetic Background:
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involves: 129 * CD-1
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Mutant Allele(s):
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Ascl1tm1And/Ascl1tm1And
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Age:
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embryonic day 12.5
|
Sex:
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Not Specified
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Type:
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section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
sagittal section
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: cerebral cortex |
Present |
|
4D
|
Expression is present in Cajal-Retzius cells. The number of expressing cells in the mutants are reduced 1.35 fold.
|
Specimen
4D':
(close )
Genetic Background:
|
involves: 129 * CD-1
|
Mutant Allele(s):
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Ascl1tm1And/Ascl1tm1And
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Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
sagittal section
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: cortical preplate |
Present |
|
4D'
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Expression is present in Cajal-Retzius cells. The number of expressing cells in the mutants are reduced 1.35 fold.
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Specimen
not shown - wild type:
embryonic day 15.5
(more )
Specimen
not shown - wild type:
(close )
Genetic Background:
|
involves: 129 * CD-1
|
Age:
|
embryonic day 15.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: cerebral cortex |
Present |
|
|
Expression is present in Cajal-Retzius cells.
|
Specimen
not shown - Ascl1-/-:
(close )
Genetic Background:
|
involves: 129 * CD-1
|
Mutant Allele(s):
|
Ascl1tm1And/Ascl1tm1And
|
Age:
|
embryonic day 15.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: cerebral cortex |
Present |
|
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Expression is present in Cajal-Retzius cells. There are fewer expressing cells in the mutant.
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Specimen
5D:
embryonic day 18.5
(more )
Note: coronal section
Specimen
5D:
(close )
Genetic Background:
|
involves: 129 * CD-1
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
coronal section
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: cerebral cortex |
Present |
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5D
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Expression is present in Cajal-Retzius cells in cortical layers II-VI.
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Specimen
5D':
embryonic day 18.5
(more )
Note: sagittal section
Specimen
5D':
(close )
Genetic Background:
|
involves: 129 * CD-1
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
sagittal section
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: cerebral cortex marginal zone |
Present |
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5D'
,
5D''
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Expression is present in Cajal-Retzius cells in the upper marginal zone and in interneurons in the lower marginal zone.
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Specimen
5E:
(close )
Genetic Background:
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involves: 129 * CD-1
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Mutant Allele(s):
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Ascl1tm1And/Ascl1tm1And
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Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
coronal section
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: cerebral cortex |
Present |
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5E
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Expression is present in Cajal-Retzius cells in cortical layers II-VI. There are fewer expressing cells in the mutant.
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Specimen
5E':
(close )
Genetic Background:
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involves: 129 * CD-1
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Mutant Allele(s):
|
Ascl1tm1And/Ascl1tm1And
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
sagittal section
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: cerebral cortex marginal zone |
Present |
|
5E'
,
5E''
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Expression is present in Cajal-Retzius cells in the upper marginal zone and in interneurons in the lower marginal zone. There are fewer expressing cells in the mutant.
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