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Gene Expression Data
Assay Details
Assay
Reference: J:188692 Dixit R, et al., Ascl1 participates in Cajal-Retzius cell development in the neocortex. Cereb Cortex. 2011 Nov;21(11):2599-611
Assay type: RNA in situ
MGI Accession ID: MGI:6404058
Gene symbol: Reln
Gene name: reelin
Probe: Reln probe9
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 4C: embryonic day 12.5 (more )
Note: sagittal section
Structure Level Pattern Image Note
TS20: cerebral cortex Present 4C Expression is present in Cajal-Retzius cells.

Specimen 4C': embryonic day 12.5 (more )
Note: sagittal section
Structure Level Pattern Image Note
TS20: cortical preplate Present 4C' Expression is present in Cajal-Retzius cells.

Specimen 4D: embryonic day 12.5; Ascl1tm1And/Ascl1tm1And (more )
Note: sagittal section
Structure Level Pattern Image Note
TS20: cerebral cortex Present 4D Expression is present in Cajal-Retzius cells. The number of expressing cells in the mutants are reduced 1.35 fold.

Specimen 4D': embryonic day 12.5; Ascl1tm1And/Ascl1tm1And (more )
Note: sagittal section
Structure Level Pattern Image Note
TS20: cortical preplate Present 4D' Expression is present in Cajal-Retzius cells. The number of expressing cells in the mutants are reduced 1.35 fold.

Specimen not shown - wild type: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex Present Expression is present in Cajal-Retzius cells.

Specimen not shown - Ascl1-/-: embryonic day 15.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS23: cerebral cortex Present Expression is present in Cajal-Retzius cells. There are fewer expressing cells in the mutant.

Specimen 5D: embryonic day 18.5 (more )
Note: coronal section
Structure Level Pattern Image Note
TS26: cerebral cortex Present 5D Expression is present in Cajal-Retzius cells in cortical layers II-VI.

Specimen 5D': embryonic day 18.5 (more )
Note: sagittal section
Structure Level Pattern Image Note
TS26: cerebral cortex marginal zone Present 5D' , 5D'' Expression is present in Cajal-Retzius cells in the upper marginal zone and in interneurons in the lower marginal zone.

Specimen 5E: embryonic day 18.5; Ascl1tm1And/Ascl1tm1And (more )
Note: coronal section
Structure Level Pattern Image Note
TS26: cerebral cortex Present 5E Expression is present in Cajal-Retzius cells in cortical layers II-VI. There are fewer expressing cells in the mutant.

Specimen 5E': embryonic day 18.5; Ascl1tm1And/Ascl1tm1And (more )
Note: sagittal section
Structure Level Pattern Image Note
TS26: cerebral cortex marginal zone Present 5E' , 5E'' Expression is present in Cajal-Retzius cells in the upper marginal zone and in interneurons in the lower marginal zone. There are fewer expressing cells in the mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory