Msx2 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:146434 Maatouk DM, et al., In the limb AER Bmp2 and Bmp4 are required for dorsal-ventral patterning and interdigital cell death but not limb outgrowth. Dev Biol. 2009 Mar 15;327(2):516-23
Assay type:	RNA in situ
MGI Accession ID:	MGI:6403991
Gene symbol:	Msx2
Gene name:	msh homeobox 2

Probe:

Msx2 probe39

Results

4C ©

Specimen 4C: embryonic day 11.5; Bmp2^tm1Cjt/Bmp2^tm1Cjt, Bmp4^tm1Jfm/Bmp4^tm1Jfm (more

)

Structure	Level	Pattern	Image	Note
TS19: footplate apical ectodermal ridge	Present		4C
TS19: footplate mesenchyme	Present		4C

4D ©

Specimen 4D: embryonic day 11.5; Bmp2^tm1Cjt/Bmp2^tm1Cjt, Bmp4^tm1Jfm/Bmp4^tm1Jfm, Tg(Msx2-cre)5Rem/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS19: footplate apical ectodermal ridge	Absent		4D
TS19: footplate mesenchyme	Weak	Regionally restricted	4D	Expression decreased in mesenchyme underlying AER.

4E ©

Specimen 4E: embryonic day 13.5; Bmp2^tm1Cjt/Bmp2^tm1Cjt, Bmp4^tm1Jfm/Bmp4^tm1Jfm (more

)

Structure	Level	Pattern	Image	Note
TS21: foot epithelium	Present		4E
TS21: foot mesenchyme	Present		4E

4F ©

Specimen 4F: embryonic day 13.5; Bmp2^tm1Cjt/Bmp2^tm1Cjt, Bmp4^tm1Jfm/Bmp4^tm1Jfm, Tg(Msx2-cre)5Rem/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS21: foot epithelium	Absent		4F	No expression in apical ectodermal ridge.
TS21: foot mesenchyme	Weak	Regionally restricted	4F	Expression decreased in mesenchyme underlying AER.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24