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Gene Expression Data
Assay Details
Assay
Reference: J:213956 Pryor SE, et al., Vangl-dependent planar cell polarity signalling is not required for neural crest migration in mammals. Development. 2014 Aug;141(16):3153-8
Assay type: RNA in situ
MGI Accession ID: MGI:6403716
Gene symbol: Erbb3
Gene name: erb-b2 receptor tyrosine kinase 3
Probe: ErbB3 probe8
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1A: embryonic day 9.5 (more )
Note: Early E9.5 embryos with 13-14 somites.
Structure Level Pattern Image Note
TS15: future hindbrain Present Regionally restricted 1A Expression is in neural crest cells migrating from the hindbrain.
TS15: migrating neural crest Present Regionally restricted 1A Expression is in neural crest cells migrating from the hindbrain.
TS15: future forebrain Present Regionally restricted 1A Expression is in migrating neural crest cells.
TS15: head mesenchyme derived from neural crest Present Regionally restricted 1A Expression is in migrating neural crest cells in the peri-ocular region.
TS15: 1st branchial arch mesenchyme derived from neural crest Present Regionally restricted 1A Expression is in migrating neural crest cells.
TS15: 2nd branchial arch mesenchyme derived from neural crest Present Regionally restricted 1A Expression is in migrating neural crest cells.

Specimen 1B: embryonic day 9.5 (more )
Note: Early E9.5 embryos with 13-14 somites.
Structure Level Pattern Image Note
TS15: future hindbrain Present Regionally restricted 1B Expression is in neural crest cells migrating from the hindbrain.
TS15: migrating neural crest Present Regionally restricted 1B Expression is in neural crest cells migrating from the hindbrain.
TS15: future forebrain Present Regionally restricted 1B Expression is in migrating neural crest cells.
TS15: head mesenchyme derived from neural crest Present Regionally restricted 1B Expression is in migrating neural crest cells in the peri-ocular region.
TS15: 1st branchial arch mesenchyme derived from neural crest Present Regionally restricted 1B Expression is in migrating neural crest cells.
TS15: 2nd branchial arch mesenchyme derived from neural crest Present Regionally restricted 1B Expression is in migrating neural crest cells.

Specimen 1C: embryonic day 9.5 (more )
Note: Early E9.5 embryos with 13-14 somites.
Structure Level Pattern Image Note
TS15: migrating neural crest Present 1C
TS15: neural tube Present Regionally restricted 1C Expression is in migrating neural crest cells.
TS15: trunk mesenchyme derived from neural crest Present Regionally restricted 1C Expression is in migrating neural crest cells.

Specimen 1D: embryonic day 9.5; Vangl2Lp/Vangl2Lp (more )
Note: Early E9.5 embryos with 13-14 somites.
Structure Level Pattern Image Note
TS15: future hindbrain Present Regionally restricted 1D Expression is in neural crest cells migrating from the hindbrain.
TS15: migrating neural crest Present Regionally restricted 1D Expression is in neural crest cells migrating from the hindbrain.
TS15: 1st branchial arch mesenchyme derived from neural crest Present Regionally restricted 1D Expression is in migrating neural crest cells.
TS15: 2nd branchial arch mesenchyme derived from neural crest Present Regionally restricted 1D Expression is in migrating neural crest cells.

Specimen 1E: embryonic day 9.5; Vangl2Lp/Vangl2Lp (more )
Note: Early E9.5 embryos with 13-14 somites.
Structure Level Pattern Image Note
TS15: future hindbrain Present Regionally restricted 1E Expression is in neural crest cells migrating from the hindbrain.
TS15: migrating neural crest Present Regionally restricted 1E Expression is in neural crest cells migrating from the hindbrain.
TS15: 1st branchial arch mesenchyme derived from neural crest Present Regionally restricted 1E Expression is in migrating neural crest cells.
TS15: 2nd branchial arch mesenchyme derived from neural crest Present Regionally restricted 1E Expression is in migrating neural crest cells.

Specimen 1F: embryonic day 9.5; Vangl2Lp/Vangl2Lp (more )
Note: Early E9.5 embryos with 13-14 somites.
Structure Level Pattern Image Note
TS15: migrating neural crest Present 1F
TS15: neural tube Present Regionally restricted 1F Expression is in migrating neural crest cells.
TS15: trunk mesenchyme derived from neural crest Present Regionally restricted 1F Expression is in migrating neural crest cells.

Specimen 2I: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: future spinal cord neural fold Present Regionally restricted 2I Expression is at the edges.

Specimen 2I': embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: future spinal cord neural fold Present Regionally restricted 2I' Expression is at the edges.

Specimen 2J: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: future spinal cord neural fold Present Regionally restricted 2J Expression is at the edges.

Specimen 2K: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: future spinal cord neural fold Present Regionally restricted 2K Expression is at the edges.

Specimen 2L: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: future spinal cord neural fold Present Regionally restricted 2L Expression is at the edges.

Specimen 3A: embryonic day 8.5; Vangl1Gt(XL802)Byg/Vangl1+, Vangl2tm1.2Yy/Vangl2+ (more )
Structure Level Pattern Image Note
TS13: migrating neural crest Present Regionally restricted 3A Expression is in cranial migrating neural crest.

Specimen 3B: embryonic day 8.5; Vangl1Gt(XL802)Byg/Vangl1Gt(XL802)Byg, Vangl2tm1.2Yy/Vangl2tm1.2Yy (more )
Structure Level Pattern Image Note
TS13: migrating neural crest Present 3B Expression in this mutant is the same as in control embryos.

Specimen 3C: embryonic day 9.5; Vangl1Gt(XL802)Byg/Vangl1+, Vangl2tm1.2Yy/Vangl2+ (more )
Structure Level Pattern Image Note
TS15: migrating neural crest Present Regionally restricted 3C Expression is in cranial and trunk migrating neural crest.

Specimen 3D: embryonic day 9.5; Vangl1Gt(XL802)Byg/Vangl1+, Vangl2tm1.2Yy/Vangl2+ (more )
Structure Level Pattern Image Note
TS15: migrating neural crest Present Regionally restricted 3D Expression is in cranial migrating neural crest.

Specimen 3E: embryonic day 9.5; Vangl1Gt(XL802)Byg/Vangl1+, Vangl2tm1.2Yy/Vangl2+ (more )
Structure Level Pattern Image Note
TS15: migrating neural crest Present Regionally restricted 3E Expression is in cranial and trunk migrating neural crest.

Specimen 3F: embryonic day 9.5; Vangl1Gt(XL802)Byg/Vangl1Gt(XL802)Byg, Vangl2tm1.2Yy/Vangl2tm1.2Yy (more )
Structure Level Pattern Image Note
TS15: migrating neural crest Present 3F Expression in this mutant is the same as in control embryos.

Specimen 3G: embryonic day 9.5; Vangl1Gt(XL802)Byg/Vangl1Gt(XL802)Byg, Vangl2tm1.2Yy/Vangl2tm1.2Yy (more )
Structure Level Pattern Image Note
TS15: migrating neural crest Present 3G Expression in this mutant is the same as in control embryos.

Specimen 3H: embryonic day 9.5; Vangl1Gt(XL802)Byg/Vangl1Gt(XL802)Byg, Vangl2tm1.2Yy/Vangl2tm1.2Yy (more )
Structure Level Pattern Image Note
TS15: migrating neural crest Present 3H Expression in this mutant is the same as in control embryos.

Specimen S1G: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: migrating neural crest Present Regionally restricted S1G Expression is in a rostral-caudal progression of neural crest cells migrating from the neural tube.
TS15: neural tube Present Regionally restricted S1G Expression is in a rostral-caudal progression of neural crest cells migrating from the neural tube.
TS15: trunk mesenchyme derived from neural crest Present Regionally restricted S1G Expression is in a rostral-caudal progression of neural crest cells migrating from the neural tube.

Specimen S1H: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: migrating neural crest Present Regionally restricted S1H Expression is in a rostral-caudal progression of neural crest cells migrating from the neural tube.
TS15: neural tube Present Regionally restricted S1H Expression is in a rostral-caudal progression of neural crest cells migrating from the neural tube.
TS15: trunk mesenchyme derived from neural crest Present Regionally restricted S1H Expression is in a rostral-caudal progression of neural crest cells migrating from the neural tube.

Specimen S1I: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: migrating neural crest Present Regionally restricted S1I Expression is in a rostral-caudal progression of neural crest cells migrating from the neural tube.
TS15: neural tube Present Regionally restricted S1I Expression is in a rostral-caudal progression of neural crest cells migrating from the neural tube.
TS15: trunk mesenchyme derived from neural crest Present Regionally restricted S1I Expression is in a rostral-caudal progression of neural crest cells migrating from the neural tube.

Specimen S1J: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: migrating neural crest Present S1J Expression is in a rostral-caudal progression of neural crest cells migrating from the neural tube.
TS15: neural tube Present S1J Expression is in a rostral-caudal progression of neural crest cells migrating from the neural tube.
TS15: trunk mesenchyme derived from neural crest Present S1J Expression is in a rostral-caudal progression of neural crest cells migrating from the neural tube.

Specimen S1K: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: migrating neural crest Present S1K Expression is in a rostral-caudal progression of neural crest cells migrating from the neural tube.
TS15: neural tube Present S1K Expression is in a rostral-caudal progression of neural crest cells migrating from the neural tube.
TS15: trunk mesenchyme derived from neural crest Present S1K Expression is in a rostral-caudal progression of neural crest cells migrating from the neural tube.

Specimen S1L: embryonic day 9.5; Vangl2Lp/Vangl2Lp (more )
Structure Level Pattern Image Note
TS15: migrating neural crest Present Regionally restricted S1L Expression in migrating neural crest cells in this mutant is similar to wild-type expression.
TS15: neural tube Present Regionally restricted S1L Expression in migrating neural crest cells in this mutant is similar to wild-type expression.
TS15: trunk mesenchyme derived from neural crest Present Regionally restricted S1L Expression in migrating neural crest cells in this mutant is similar to wild-type expression.

Specimen S1M: embryonic day 9.5; Vangl2Lp/Vangl2Lp (more )
Structure Level Pattern Image Note
TS15: migrating neural crest Present Regionally restricted S1M Expression in migrating neural crest cells in this mutant is similar to wild-type expression.
TS15: neural tube Present Regionally restricted S1M Expression in migrating neural crest cells in this mutant is similar to wild-type expression.
TS15: trunk mesenchyme derived from neural crest Present Regionally restricted S1M Expression in migrating neural crest cells in this mutant is similar to wild-type expression.

Specimen S1N: embryonic day 9.5; Vangl2Lp/Vangl2Lp (more )
Structure Level Pattern Image Note
TS15: migrating neural crest Present Regionally restricted S1N Expression in migrating neural crest cells in this mutant is similar to wild-type expression.
TS15: neural tube Present Regionally restricted S1N Expression in migrating neural crest cells in this mutant is similar to wild-type expression.
TS15: trunk mesenchyme derived from neural crest Present Regionally restricted S1N Expression in migrating neural crest cells in this mutant is similar to wild-type expression.

Specimen S1O: embryonic day 9.5; Vangl2Lp/Vangl2Lp (more )
Structure Level Pattern Image Note
TS15: migrating neural crest Present Regionally restricted S1O Expression in migrating neural crest cells in this mutant is similar to wild-type expression.
TS15: neural tube Present Regionally restricted S1O Expression in migrating neural crest cells in this mutant is similar to wild-type expression.
TS15: trunk mesenchyme derived from neural crest Present Regionally restricted S1O Expression in migrating neural crest cells in this mutant is similar to wild-type expression.

Specimen S1P: embryonic day 9.5; Vangl2Lp/Vangl2Lp (more )
Structure Level Pattern Image Note
TS15: migrating neural crest Present Regionally restricted S1P Expression in migrating neural crest cells in this mutant is similar to wild-type expression.
TS15: neural tube Present Regionally restricted S1P Expression in migrating neural crest cells in this mutant is similar to wild-type expression.
TS15: trunk mesenchyme derived from neural crest Present Regionally restricted S1P Expression in migrating neural crest cells in this mutant is similar to wild-type expression.

Specimen S1Q: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: migrating neural crest Present Regionally restricted S1Q , S1R Expression in migrating neural crest cells.
TS17: trunk mesenchyme derived from neural crest Present Regionally restricted S1Q , S1R Expression in migrating neural crest cells.

Specimen S1S: embryonic day 10.5; Vangl2Lp/Vangl2Lp (more )
Structure Level Pattern Image Note
TS17: migrating neural crest Present S1T , S1S Expression in this mutant is similar to wild-type expression.
TS17: trunk mesenchyme derived from neural crest Present S1T , S1S Expression in this mutant is similar to wild-type expression.

Specimen S1U: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: facio-acoustic ganglion complex Present S1V , S1U
TS17: glossopharyngeal ganglion Present S1V , S1U
TS17: trigeminal ganglion Present S1V , S1U
TS17: vagus ganglion Present S1V , S1U
TS17: dorsal root ganglion Present S1U

Specimen S1W: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present S1W

Specimen S1X: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present S1X

Specimen S1Y: embryonic day 10.5; Vangl2Lp/Vangl2Lp (more )
Structure Level Pattern Image Note
TS17: facio-acoustic ganglion complex Present S1Y , S1Z Expression in this mutant is similar to wild-type expression.
TS17: glossopharyngeal ganglion Present S1Y , S1Z Expression in this mutant is similar to wild-type expression.
TS17: trigeminal ganglion Present S1Y , S1Z Expression in this mutant is similar to wild-type expression.
TS17: vagus ganglion Present S1Y , S1Z Expression in this mutant is similar to wild-type expression.
TS17: dorsal root ganglion Present S1Y Expression in this mutant is similar to wild-type expression.

Specimen S1AA: embryonic day 10.5; Vangl2Lp/Vangl2Lp (more )
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present S1AA Expression in this mutant is similar to wild-type expression.

Specimen S1BB: embryonic day 10.5; Vangl2Lp/Vangl2Lp (more )
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present S1BB Expression in this mutant is similar to wild-type expression.

Specimen S3G: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: head mesenchyme derived from neural crest Present Regionally restricted S3G Expression is in migrating neural crest in the cranio-facial region and the trunk.
TS15: migrating neural crest Present Regionally restricted S3G Expression is in migrating neural crest in the cranio-facial region and the trunk.
TS15: trunk mesenchyme derived from neural crest Present Regionally restricted S3G Expression is in migrating neural crest in the cranio-facial region and the trunk.

Specimen S3H: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: migrating neural crest Present Regionally restricted S3H Expression is in migrating neural crest in the trunk.
TS15: trunk mesenchyme derived from neural crest Present Regionally restricted S3H Expression is in migrating neural crest in the trunk.

Specimen S3I: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: migrating neural crest Present Regionally restricted S3I Expression is in migrating neural crest in the trunk.
TS15: trunk mesenchyme derived from neural crest Present Regionally restricted S3I Expression is in migrating neural crest in the trunk.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory