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Tg(Eno2-Agtr1a)6085-2Sig
Transgene Detail
Summary
Symbol: Tg(Eno2-Agtr1a)6085-2Sig
Name: transgene insertion 6085-2, Curt D Sigmund
MGI ID: MGI:6403682
Synonyms: NSE-AT1a
Transgene: Tg(Eno2-Agtr1a)6085-2Sig  Location: unknown  
Alliance: Tg(Eno2-Agtr1a)6085-2Sig page
Transgene
origin
Strain of Origin:  (C57BL/6J SJL/J)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsA consruct consisting of 4 kb of the rat neuron-specific enolase (Eno2) 5 flanking region and a cDNA encoding the full open-reading frame of the rat Agtr1a receptor was used to create transgenic mice. Three lines were created, with line 6085-2 showing brain-specific expression. (J:134569)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:134569 Lazartigues E, et al., Brain-selective overexpression of angiotensin (AT1) receptors causes enhanced cardiovascular sensitivity in transgenic mice. Circ Res. 2002 Mar 22;90(5):617-24
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory