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Gene Expression Data
Assay Details
Assay
Reference: J:36366 Ang HL, et al., Expression patterns of class I and class IV alcohol dehydrogenase genes in developing epithelia suggest a role for alcohol dehydrogenase in local retinoic acid synthesis. Alcohol Clin Exp Res. 1996 Sep;20(6):1050-64
Assay type: RNA in situ
MGI Accession ID: MGI:6403339
Gene symbol: Adh7
Gene name: alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
Probe: Class IV ADH cDNA1
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Assay notes: Two probes were described: full length MGI:6403329 and shorter MGI:6403331. Both gave identical results.
Results
Specimen 1D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: embryo Absent 1D
Specimen 1H: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: embryo Absent 1H
Specimen 1L: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: adrenal gland Present 1L
TS22: liver Trace 1L The low signal in the liver was not consistently above background.
Specimen 2C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: nasal epithelium Present 2C
Specimen 2F: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: adrenal gland Present 2F
Specimen 3D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: adrenal gland Present 3D
Specimen 4C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: liver Absent 4C
Specimen 4G: postnatal adult (more )
Structure Level Pattern Image Note
TS28: metanephros Ambiguous Diffuse 4G A diffuse unlocalized signal above background was detected. However, authors indicated concern that it was a real signal. Previous Northern results have shown this tissue should be absent.
Specimen 4K: postnatal adult (more )
Structure Level Pattern Image Note
TS28: adrenal cortex Present 4K
TS28: adrenal medulla Absent 4K
TS28: adrenal gland zona reticularis Trace 4K
TS28: adrenal gland zona fasciculata Present Non-Uniform 4K Expression was detected as a striped pattern.
Specimen 5B: postnatal adult (more )
Structure Level Pattern Image Note
TS28: esophagus basal epithelium Present 5C , 5B
TS28: esophagus lamina propria Absent 5B , 5C
TS28: esophagus muscularis Absent 5B , 5C
TS28: esophagus squamous epithelium Absent 5C , 5B Signal was absent from surface epithelial cells being shed into the lumen.
Specimen 5F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: stomach Present 5F
Specimen 5G: postnatal adult (more )
Structure Level Pattern Image Note
TS28: stomach epithelium Present Regionally restricted 5G Expression was detected in the mucous-secreting epithelium lining the gastric pits.
TS28: stomach muscularis externa Absent 5G
TS28: stomach fundus gastric gland Absent 5G Signal was absent in the regions containing the chief cells (pepsin-secreting cells).
Specimen 5J: postnatal adult (more )
Structure Level Pattern Image Note
TS28: small intestine Absent 5J
Specimen 5N: postnatal adult (more )
Structure Level Pattern Image Note
TS28: large intestine Absent 5N
Specimen 6C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: epididymis Present 6C
TS28: testis Present 6C
Specimen 6F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: seminiferous tubule epithelium Present Regionally restricted 6F The irregular shape of the expression pattern indicated the elongating spermatids were labeled.
TS28: spermatid Present 6F
TS28: spermatozoon Absent 6F
Specimen 6I: postnatal adult (more )
Structure Level Pattern Image Note
TS28: epithelium of epididymis Present Regionally restricted 6I Expression was detected in the basal cells.
TS28: spermatozoon Absent 6I
Specimen not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: ovary follicle Absent
TS28: uterus Absent
TS28: corpus luteum Weak
TS28: mesenchymal stroma of ovary Weak
Specimen 7B: postnatal adult (more )
Structure Level Pattern Image Note
TS28: skin Present 7B
Specimen 7D: postnatal adult (more )
Structure Level Pattern Image Note
TS28: epidermis Present 7D
TS28: hair follicle Present 7D
TS28: dermis Absent 7D
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory