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Gene Expression Data
Assay Details
Assay
Reference: J:191972 Huang S, et al., Wls is expressed in the epidermis and regulates embryonic hair follicle induction in mice. PLoS One. 2012;7(9):e45904
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6403123
Gene symbol: Lef1
Gene name: lymphoid enhancer binding factor 1
Antibody: anti-Lef1
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 4A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: epidermis Present 4A
TS21: dermis Present Regionally restricted 4A Expressed in the mesenchyme underlying the surface ectoderm.
Specimen 4B: embryonic day 13.5; Wlstm1Xzg/Wlstm1Xzg, Krt14tm1(cre)Wbm/Krt14+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: epidermis Present 4B Decreased expression compared with the wild-type control.
TS21: dermis Absent 4B
Specimen 4C: postnatal day 8 (more )
Structure Level Pattern Image Note
TS28: hair follicle bulge Present 4C
TS28: hair inner root sheath Present 4C
TS28: hair outer root sheath Present 4C
Specimen 4D: postnatal day 8; Wlstm1Xzg/Wlstm1Xzg, Krt14tm1(cre)Wbm/Krt14+ (more )
Note: Conditional mutant. hairless skin
Structure Level Pattern Image Note
TS28: hair follicle bulge Present 4D
TS28: hair inner root sheath Absent 4D
TS28: hair outer root sheath Absent 4D
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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