About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:191972 Huang S, et al., Wls is expressed in the epidermis and regulates embryonic hair follicle induction in mice. PLoS One. 2012;7(9):e45904
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6403123
Gene symbol: Lef1
Gene name: lymphoid enhancer binding factor 1
Antibody: anti-Lef1
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 4A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: epidermis Present 4A
TS21: dermis Present Regionally restricted 4A Expressed in the mesenchyme underlying the surface ectoderm.

Specimen 4B: embryonic day 13.5; Wlstm1Xzg/Wlstm1Xzg, Krt14tm1(cre)Wbm/Krt14+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: epidermis Present 4B Decreased expression compared with the wild-type control.
TS21: dermis Absent 4B

Specimen 4C: postnatal day 8 (more )
Structure Level Pattern Image Note
TS28: hair follicle bulge Present 4C
TS28: hair inner root sheath Present 4C
TS28: hair outer root sheath Present 4C

Specimen 4D: postnatal day 8; Wlstm1Xzg/Wlstm1Xzg, Krt14tm1(cre)Wbm/Krt14+ (more )
Note: Conditional mutant. hairless skin
Structure Level Pattern Image Note
TS28: hair follicle bulge Present 4D
TS28: hair inner root sheath Absent 4D
TS28: hair outer root sheath Absent 4D


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory