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Gene Expression Data
Assay Details
Assay
Reference: J:145030 Raffel GD, et al., Ott1 (Rbm15) is essential for placental vascular branching morphogenesis and embryonic development of the heart and spleen. Mol Cell Biol. 2009 Jan;29(2):333-41
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6402809
Gene symbol: Cd34
Gene name: CD34 antigen
Results
Specimen 2C wild type: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: syncytiotrophoblast Present Regionally restricted 2C wild type Expression was detected in the vasculature.

Specimen 2C Ott1 null: embryonic day 8.5; Rbm15tm1.1Dgg/Rbm15tm1.1Dgg (more )
Structure Level Pattern Image Note
TS13: syncytiotrophoblast Trace 2C Ott1 null Staining showed a nearly complete lack of vascularization of the syncytiotrophoblast layer.

Specimen 2E wild type: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: labyrinthine zone Present 2E wild type Expression was detected in the vaculature.

Specimen 2E Ott1 null: embryonic day 9.5; Rbm15tm1.1Dgg/Rbm15tm1.1Dgg (more )
Structure Level Pattern Image Note
TS15: labyrinthine zone Absent 2E Ott1 null The mutant labyrinth was not vascularized.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory