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Gene Expression Data
Assay Details
Assay
Reference: J:273516 Laguesse S, et al., Loss of Elp3 Impairs the Acetylation and Distribution of Connexin-43 in the Developing Cerebral Cortex. Front Cell Neurosci. 2017;11:122
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6401819
Gene symbol: Gja1
Gene name: gap junction protein, alpha 1
Antibody: anti-Cx43 IF1
Detection system: Secondary antibody coupled to rhodamine
Assay notes: This antibody detects only the membrane expression.
Results
Specimen 6A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex Present Widespread 6A Membrane labeling throughout the cortical wall with some accumulation detected in the ventricular/subventricular zones, as compared to the intermediate zone and cortical plate.
TS22: cerebral cortex subventricular zone Present 6E , 6F , 6C , 6D , 6A Some accumulation detected in the ventricular/subventricular zones, as compared to the intermediate zone and cortical plate.
TS22: cerebral cortex ventricular layer Present 6E , 6F , 6C , 6D , 6A Some accumulation detected in the ventricular/subventricular zones, as compared to the intermediate zone and cortical plate.
TS22: cerebral cortex intermediate zone Present Uniform 6A , 6B Membrane labeling throughout the cortical wall. Less accumulation as compared to the ventricular/subventricular zones.
TS22: cortical plate Present Uniform 6A , 6B Membrane labeling throughout the cortical wall. Less accumulation as compared to the ventricular/subventricular zones.
Specimen 6G: embryonic day 14.5; Elp3tm1.1Tac/Elp3tm1.1Tac, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: cerebral cortex intermediate zone Weak 6H , 6G Reduced expression compared to the wild-type littermate.
TS22: cortical plate Weak 6H , 6G Reduced expression compared to the wild-type littermate.
TS22: cerebral cortex ventricular layer Present 6G , 6K , 6I , 6J , 6L Increased membrane distribution compared to the wild-type littermate.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory