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Gene Expression Data
Assay Details
Assay
Reference: J:56117 Noakes PG, et al., Expression and localisation of dynamin and syntaxin during neural development and neuromuscular synapse formation. J Comp Neurol. 1999 Aug 9;410(4):531-40
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6401339
Gene symbol: Dnm1
Gene name: dynamin 1
Antibody: anti-rat dynamin I (DP-4.1)
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 5B: postnatal adult (more )
Note: Summarized in Table 1.
Structure Level Pattern Image Note
TS28: intercostal muscle Present Clusters 5B Expression was concentrated at AChR clusters (85% colocalised with alpha-bungarotoxin).
TS28: intercostal nerve Present Clusters 5B Expression was concentrated at AChR clusters (85% colocalised with alpha-bungarotoxin).
Specimen 5D: embryonic day 17.5 (more )
Note: Summarized in Table 1.
Structure Level Pattern Image Note
TS25: intercostal muscle Present Clusters 5D Expression became concentrated at most neuromuscular synapses (69% colocalised with alpha-bungarotoxin).
TS25: intercostal nerve Present Clusters 5D Expression became concentrated at most neuromuscular synapses (69% colocalised with alpha-bungarotoxin).
Specimen 5H: postnatal adult (more )
Structure Level Pattern Image Note
TS28: peripheral nerve Present Regionally restricted 5H Expressed in neuromuscular synapses.
TS28: skeletal muscle Present Regionally restricted 5H Expressed in neuromuscular synapses.
Specimen 6B: embryonic day 14.5 (more )
Note: Summarized in Table 1.
Structure Level Pattern Image Note
TS22: intercostal muscle Present Regionally restricted 6B Only occasionally detected with AChR clusters (3% colocalised with alpha-bungarotoxin).
TS22: intercostal nerve Present Regionally restricted 6B Only occasionally detected with AChR clusters (3% colocalised with alpha-bungarotoxin).
Specimen not shown: embryonic day 14.0 (more )
Note: Summarized in Table 1.
Structure Level Pattern Image Note
TS22: intercostal muscle Absent No expression in AChR clusters (0/54).
TS22: intercostal nerve Absent No expression in AChR clusters (0/54).
Specimen not shown: embryonic day 15.5 (more )
Note: Summarized in Table 1.
Structure Level Pattern Image Note
TS23: intercostal muscle Present Clusters Expression was concentrated at AChR clusters (30% colocalised with alpha-bungarotoxin).
TS23: intercostal nerve Present Clusters Expression was concentrated at AChR clusters (30% colocalised with alpha-bungarotoxin).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory