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Gene Expression Data
Assay Details
Assay
Reference: J:233748 Yzaguirre AD, et al., Extravascular endothelial and hematopoietic islands form through multiple pathways in midgestation mouse embryos. Dev Biol. 2016 Jul 1;415(1):111-21
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6400721
Gene symbol: Runx1
Gene name: runt related transcription factor 1
Results
Specimen 2A: embryonic day 10.5 (more )
Note: Double labeled: green - Runx1; red - CD31 (Pecam1 assay MGI:6400720).
Structure Level Pattern Image Note
TS17: umbilical artery Present 2A
TS17: vitelline artery Present 2A
TS17: hematopoietic system Present Regionally restricted 2A Expression in extravascular islands in region between vitelline and umbilical arteries in the embryo proper.

Specimen 2Ai/iii: embryonic day 10.5 (more )
Note: Double labeled: green - Runx1; red - CD31 (Pecam1 assay MGI:6400720).
Structure Level Pattern Image Note
TS17: umbilical artery Present 2Ai , 2Aiii
TS17: vitelline artery Present 2Ai , 2Aiii
TS17: hematopoietic system Present Regionally restricted 2Ai , 2Aiii Expression in extravascular islands in region between vitelline and umbilical arteries in the embryo proper.

Specimen 4Ai/iii: embryonic day 10.5 (more )
Note: 36 somite pairs. Triple labeled: green - Runx1; red - CD31 (Pecam1 assay MGI:6400720); blue - Kit (assay MGI:6400722).
Structure Level Pattern Image Note
TS17: vitelline artery Present 4Ai , 4Aiii
TS17: hematopoietic system Present Regionally restricted 4Ai , 4Aiii Expression in a large type III extravascular island between vitelline artery and vascular plexus.

Specimen 4Bi/iii: embryonic day 10.5 (more )
Note: 36 somite pairs. Triple labeled: green - Runx1; red - CD31 (Pecam1 assay MGI:6400720); blue - Kit (assay MGI:6400722).
Structure Level Pattern Image Note
TS17: hematopoietic system Present Regionally restricted 4Bi , 4Biii Expression in a large type III extravascular island between vitelline artery and vascular plexus.

Specimen 4Ci/iii: embryonic day 10.5 (more )
Note: 36 somite pairs. Triple labeled: green - Runx1; red - CD31 (Pecam1 assay MGI:6400720); blue - Kit (assay MGI:6400722).
Structure Level Pattern Image Note
TS17: hematopoietic system Present Regionally restricted 4Ci , 4Ciii Expression in a large type III extravascular island between vitelline artery and vascular plexus.

Specimen 4Fii: embryonic day 11.5 (more )
Note: 46 somite pairs. Triple labeled: green - Runx1; red - CD31 (Pecam1 assay MGI:6400720); blue - Kit (assay MGI:6400722).
Structure Level Pattern Image Note
TS19: hematopoietic system Present Regionally restricted 4Fii Expression in a type III extravascular island at base of umbilical artery where it connects to the placenta.

Specimen 4Fii inset: embryonic day 11.5 (more )
Note: 46 somite pairs. Triple labeled: green - Runx1; red - CD31 (Pecam1 assay MGI:6400720); blue - Kit (assay MGI:6400722).
Structure Level Pattern Image Note
TS19: hematopoietic system Present Regionally restricted 4Fii inset Expression in a type III extravascular island at base of umbilical artery where it connects to the placenta.

Specimen 5Aii: embryonic day 10.0 (more )
Note: 34 somite pairs. Triple labeled: green - Runx1; red - CD31 (Pecam1 assay MGI:6400720); blue - Kit (assay MGI:6400722).
Structure Level Pattern Image Note
TS16: hematopoietic system Present Regionally restricted 5Aii Expression in hematopoietic clusters.

Specimen 5Bii: embryonic day 10.0 (more )
Note: 32 somite pairs. Triple labeled: green - Runx1; red - CD31 (Pecam1 assay MGI:6400720); blue - Kit (assay MGI:6400722).
Structure Level Pattern Image Note
TS16: hematopoietic system Present Regionally restricted 5Bii Expression in hematopoietic clusters.

Specimen 6A Umbilical Artery: embryonic day 10.5 (more )
Note: 34-36 somite pairs. Triple labeled: green - Runx1; red - CD31 (Pecam1 assay MGI:6400720); blue - Kit (assay MGI:6400722).
Structure Level Pattern Image Note
TS17: hematopoietic system Present Regionally restricted 6Aiii (top) , 6Ai (top) Expression in hematopoietic clusters.

Specimen 6A Dorsal Aorta: embryonic day 10.5 (more )
Note: 34-36 somite pairs. Triple labeled: green - Runx1; red - CD31 (Pecam1 assay MGI:6400720); blue - Kit (assay MGI:6400722).
Structure Level Pattern Image Note
TS17: hematopoietic system Present Regionally restricted 6Aiii (bottom) , 6Ai (bottom) Expression in hematopoietic clusters.

Specimen 8D: embryonic day 10.5 (more )
Note: 36 somite pairs. Triple labeled: white - Runx1; red - CD31 (Pecam1 assay MGI:6400720); green - Kit (assay MGI:6400722).
Structure Level Pattern Image Note
TS17: hematopoietic system Present Regionally restricted 8D Expression in large elongated type II, III and IV extravascular islands on cranial side of umbilical artery.

Specimen 8E: embryonic day 10.5 (more )
Note: 36 somite pairs. Triple labeled: white - Runx1; red - CD31 (Pecam1 assay MGI:6400720); green - Kit (assay MGI:6400722).
Structure Level Pattern Image Note
TS17: hematopoietic system Present Regionally restricted 8E Expression in large elongated type II, III and IV extravascular islands on cranial side of umbilical artery.

Specimen 8F: embryonic day 10.5 (more )
Note: 36 somite pairs. Triple labeled: white - Runx1; red - CD31 (Pecam1 assay MGI:6400720); green - Kit (assay MGI:6400722).
Structure Level Pattern Image Note
TS17: hematopoietic system Present Regionally restricted 8F Expression in large elongated type II, III and IV extravascular islands on cranial side of umbilical artery. Some extravascular islands are connected to small diameter vessels running parallel to the umbilical artery.

Specimen 8J: embryonic day 10.0 (more )
Note: 32 somite pairs. Triple labeled: white - Runx1; red - CD31 (Pecam1 assay MGI:6400720); green - Kit (assay MGI:6400722).
Structure Level Pattern Image Note
TS17: hematopoietic system Present Regionally restricted 8J Expression in a cluster of hematopoietic cells connected to the small vessel.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory