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Gene Expression Data
Assay Details
Assay
Reference: J:160585 Kesper DA, et al., Gli2 activator function in preosteoblasts is sufficient to mediate Ihh-dependent osteoblast differentiation, whereas the repressor function of Gli2 is dispensable for endochondral ossification. Dev Dyn. 2010 Jun;239(6):1818-26
Assay type: RNA in situ
MGI Accession ID: MGI:6394018
Gene symbol: Col10a1
Gene name: collagen, type X, alpha 1
Probe: Col10a1 probe2
Probe preparation: Antisense labelled with P33 RNA
Results
Specimen 1I: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: forelimb cartilage condensation Present Regionally restricted 1I Expression is in distinct zones of hypertrophic chondrocytes.

Specimen 1J: embryonic day 16.5; Ihhtm1Amc/Ihhtm1Amc (more )
Structure Level Pattern Image Note
TS24: forelimb cartilage condensation Present Regionally restricted 1J There is a central region of expression in this mutant.

Specimen 1K: embryonic day 16.5; Gli2tm6Alj/Gli2tm6Alj, Ihhtm1Amc/Ihhtm1Amc, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: forelimb cartilage condensation Present Regionally restricted 1K There is a central region of expression in this mutant.

Specimen 1L: embryonic day 16.5; Gli2tm6Alj/Gli2tm6Alj, Ihhtm1Amc/Ihhtm1Amc, Tg(COL2A1-cre)1Wag/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: forelimb cartilage condensation Present Regionally restricted 1L There is a central region of expression in this mutant.

Specimen 2E: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: forelimb cartilage condensation Present Regionally restricted 2E Expression is in distinct zones of hypertrophic chondrocytes.

Specimen 2F: embryonic day 16.5; Gli3Xt-J/Gli3Xt-J, Ihhtm1Amc/Ihhtm1Amc (more )
Structure Level Pattern Image Note
TS24: forelimb cartilage condensation Present Regionally restricted 2F There is a central region of expression in this mutant.

Specimen 2G: embryonic day 16.5; Gli2tm6Alj/Gli2tm6Alj, Gli3Xt-J/Gli3Xt-J, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: forelimb cartilage condensation Present Regionally restricted 2G There is a central region of expression in this mutant.

Specimen 2H: embryonic day 16.5; Gli2tm6Alj/Gli2tm6Alj, Gli3Xt-J/Gli3Xt-J, Tg(COL2A1-cre)1Wag/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: forelimb cartilage condensation Present Regionally restricted 2H There is a central region of expression in this mutant.

Specimen 3C: embryonic day 16.5; Gli2tm6Alj/Gli2tm6Alj (more )
Structure Level Pattern Image Note
TS24: forelimb cartilage condensation Present Regionally restricted 3C Expression in this mutant is similar to wild-type embryos.

Specimen 3D: embryonic day 16.5; Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS24: forelimb cartilage condensation Present Regionally restricted 3D Expression in this mutant is similar to wild-type embryos.

Specimen 4A: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: forelimb cartilage condensation Present Regionally restricted 4A Expression is in hypertrophic chondrocytes.

Specimen 4B: embryonic day 18.5; Gli3Xt-J/Gli3Xt-J, Ihhtm1Amc/Ihhtm1Amc (more )
Structure Level Pattern Image Note
TS26: forelimb cartilage condensation Present 4B

Specimen 4C: embryonic day 18.5; Gli2tm6Alj/Gli2tm6Alj, Gli3Xt-J/Gli3Xt-J, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: forelimb cartilage condensation Present 4C

Specimen 4D: embryonic day 18.5; Gli2tm6Alj/Gli2tm6Alj, Gli3Xt-J/Gli3Xt-J, Tg(COL2A1-cre)1Wag/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: forelimb cartilage condensation Present 4D


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory