Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(tetO-RNAi:Ptpn22,UBC-tetR,-GFP)P2Kslr
Name:	transgene lentiviral insertion P2, Stephen Kissler
MGI ID:	MGI:6393968
Transgene:	Tg(tetO-RNAi:Ptpn22,UBC-tetR,-GFP)P2Kslr  Location: unknown
Alliance:	Tg(tetO-RNAi:Ptpn22,UBC-tetR,-GFP)P2Kslr page

Strain of Origin:

NOD

Transgene Type:    Transgenic (Inducible, Knockdown, Reporter) Mutation:    Insertion   Tg(tetO-RNAi:Ptpn22,UBC-tetR,-GFP)P2Kslr involves 1 genes/genome features (Ptpn22) View all   Mutation details: The tetracycline promoter drives inducible expression of the short hairpin RNA targeting Ptpn22 (GATGAGGATTCCAGTTATA in line P2). A human ubiquitin C promoter drives ubiquitous expression of the tetracycline repressor and a GFP reporter gene. (J:208596)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:208596 Zheng P, et al., PTPN22 silencing in the NOD model indicates the type 1 diabetes-associated allele is not a loss-of-function variant. Diabetes. 2013 Mar;62(3):896-904
All:	1 reference(s)