Shh RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:74136 Borges AC, et al., The BMP antagonists cerberus-like and noggin do not interact during mouse forebrain development. Int J Dev Biol. 2001 Apr;45(2):441-4
Assay type:	RNA in situ
MGI Accession ID:	MGI:6393701
Gene symbol:	Shh
Gene name:	sonic hedgehog

Probe:	Shh probe164
Probe preparation:	Antisense RNA

Results

Specimen 3A: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: diencephalon	Present	Regionally restricted	3A	Expression is ventral.
TS17: midbrain	Present	Regionally restricted	3A	Expression is ventral.
TS17: forelimb bud	Present	Regionally restricted	3A	Expression is in the zone of polarizing activity.
TS17: neural tube floor plate	Present		3A
TS17: notochord	Present		3A

Specimen 3B: embryonic day 10.5; Cer1^tm1Belo/Cer1⁺, Nog^tm1Amc/Nog^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS17: forebrain	Present	Regionally restricted	3B	Expression in this tissue is the same as in wild-type embryos.
TS17: forelimb bud	Present	Regionally restricted	3B	Expression in this tissue is the same as in wild-type embryos.
TS17: midbrain	Present	Regionally restricted	3B	Expression in this tissue is the same as in wild-type embryos.
TS17: neural tube	Present	Regionally restricted	3B	Expression in this tissue is the same as in wild-type embryos.
TS17: notochord	Present	Regionally restricted	3B	Expression in this tissue is the same as in wild-type embryos.

Specimen 3C: embryonic day 10.5; Cer1^tm1Belo/Cer1^tm1Belo, Nog^tm1Amc/Nog^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS17: forebrain	Present	Regionally restricted	3C	Expression in this mutant is the same as in wild-type embryos.
TS17: forelimb bud	Present	Regionally restricted	3C	Expression in this mutant is the same as in wild-type embryos.
TS17: midbrain	Present	Regionally restricted	3C	Expression in this mutant is the same as in wild-type embryos.
TS17: neural tube	Present	Regionally restricted	3C	Expression in this mutant is the same as in wild-type embryos.
TS17: notochord	Present	Regionally restricted	3C	Expression in this mutant is the same as in wild-type embryos.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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