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Gene Expression Data
Assay Details
Assay
Reference: J:190431 Suzuki Y, et al., Development of gustatory papillae in the absence of Six1 and Six4. J Anat. 2011 Dec;219(6):710-21
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6393517
Gene symbol: Uchl1
Gene name: ubiquitin carboxy-terminal hydrolase L1
Antibody: anti-PGP 9.5
Detection system: horseradish peroxidase
Results
Specimen 4A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: tongue papillary placode Present Regionally restricted 4A Authors report nerve fibers seen in presumptive circumvallate papilla.

Specimen 4B: embryonic day 13.5; Six1tm1Kwk/Six1tm1Kwk, Six4tm1Kwk/Six4tm1Kwk (more )
Structure Level Pattern Image Note
TS21: tongue papillary placode Absent 4B No nerve fibers seen in presumptive circumvallate papilla of double mutant.

Specimen 4C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: circumvallate papillae Present Regionally restricted 4C Authors report abundant nerve fibers entering core of papilla.

Specimen 4D: embryonic day 14.5; Six1tm1Kwk/Six1tm1Kwk, Six4tm1Kwk/Six4tm1Kwk (more )
Structure Level Pattern Image Note
TS22: circumvallate papillae Absent 4D No nerve fibers seen in double mutant.

Specimen 4I: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: circumvallate papillae Present Regionally restricted 4I Numerous nerve fibers in both epithelium and mesenchyme.

Specimen 4J: embryonic day 15.0; Six1tm1Kwk/Six1tm1Kwk, Six4tm1Kwk/Six4tm1Kwk (more )
Structure Level Pattern Image Note
TS23: circumvallate papillae Absent 4J No nerve fibers seen in double mutant.

Specimen 6C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: tongue epithelium Present Regionally restricted 6C Nerve fibers seen entering mesenchymal core of presumptive foliate papilla.

Specimen 6D: embryonic day 15.5; Six1tm1Kwk/Six1tm1Kwk, Six4tm1Kwk/Six4tm1Kwk (more )
Structure Level Pattern Image Note
TS23: tongue epithelium Absent 6D No nerve fibers seen among trenches of presumptive foliate papilla.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory