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Gene Expression Data
Assay Details
Assay
Reference: J:190431 Suzuki Y, et al., Development of gustatory papillae in the absence of Six1 and Six4. J Anat. 2011 Dec;219(6):710-21
Assay type: RNA in situ
MGI Accession ID: MGI:6393514
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh probe163
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: tongue papillary placode Present Regionally restricted 3E Expression in primordium epithelium of fungiform papilla.
Specimen 3F: embryonic day 12.5; Six1tm1Kwk/Six1tm1Kwk, Six4tm1Kwk/Six4tm1Kwk (more )
Structure Level Pattern Image Note
TS20: tongue papillary placode Present Regionally restricted 3F Expression in primordium epithelium of fungiform papilla , more widely expressed in double mutant than in wild type.
Specimen E13.5: embryonic day 13.5; Six1tm1Kwk/Six1tm1Kwk, Six4tm1Kwk/Six4tm1Kwk (more )
Structure Level Pattern Image Note
TS21: tongue papillary placode Present Regionally restricted Authors state expression became focused in papillary epithelium.
Specimen 4O: embryonic day 19.0 (more )
Structure Level Pattern Image Note
TS26: circumvallate papillae Present Regionally restricted 4O Expression in taste buds, trenches and von Ebner's glands.
Specimen 4P: embryonic day 19.0; Six1tm1Kwk/Six1tm1Kwk, Six4tm1Kwk/Six4tm1Kwk (more )
Structure Level Pattern Image Note
TS26: circumvallate papillae Present Regionally restricted 4P Expresison in bottom of longer trenches, but not in shorter ones.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory