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Gene Expression Data
Assay Details
Assay
Reference: J:171621 Kopecky B, et al., Conditional deletion of N-Myc disrupts neurosensory and non-sensory development of the ear. Dev Dyn. 2011 Jun;240(6):1373-90
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6392878
Gene symbol: Myo7a
Gene name: myosin VIIA
Antibody: anti-myosin VIIa (#25-6790)
Detection system: Secondary antibody coupled to Alexa Fluor 532
Results
Specimen 4B' inset: postnatal day 7; Mycntm1Psk/Mycntm1Psk, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant. Fix: 0.4% paraformaldehyde.
Structure Level Pattern Image Note
TS28: cochlea Present Regionally restricted 4B' inset Expression was detected in an ectopic patch of hair cells near the base of the cochlea.

Specimen 4E inset: postnatal day 7; Mycntm1Psk/Mycntm1Psk, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant. Fix: 0.4% paraformaldehyde.
Structure Level Pattern Image Note
TS28: cochlea Present Regionally restricted 4E inset Expression was detected in the malformed apex.

Specimen 5C': postnatal day 7; Mycntm1Psk/Mycntm1Psk, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant. Fix: 0.4% paraformaldehyde.
Structure Level Pattern Image Note
TS28: cochlea Present Regionally restricted 5C' Expression was detected in an ectopic patch of hair cells near the base of the cochlea.

Specimen 5C": postnatal day 7; Mycntm1Psk/Mycntm1Psk, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant. Fix: 0.4% paraformaldehyde.
Structure Level Pattern Image Note
TS28: cochlea Present Regionally restricted 5C'' Expression was detected in an ectopic patch of hair cells near the base of the cochlea.

Specimen 5D: postnatal day 7; Mycntm1Psk/Mycntm1Psk, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant. Fix: 0.4% paraformaldehyde. Double labeled: green - Myo7a; red - afferents.
Structure Level Pattern Image Note
TS28: cochlea Present Regionally restricted 5D" , 5D Expression was detected in hair cells in the apex.

Specimen not shown Control: postnatal day 0 (more )
Note: Fix: 0.4% paraformaldehyde.
Structure Level Pattern Image Note
TS27: cochlea Present Regionally restricted Myo7a-labeled hair cells were quantitated in Table 2.

Specimen not shown Pax2-Cre::N-Myc CKO: postnatal day 0; Mycntm1Psk/Mycntm1Psk, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant. Fix: 0.4% paraformaldehyde.
Structure Level Pattern Image Note
TS27: cochlea Present Regionally restricted Myo7a-labeled hair cells were quantitated in Table 2.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory