Tg(Prnp-APPSweOsa)#Luk
Transgene Detail
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| Symbol: |
Tg(Prnp-APPSweOsa)#Luk |
| Name: |
transgene insertion, Luka Kulic |
| MGI ID: |
MGI:6378818 |
| Synonyms: |
E22DeltaAbeta |
| Transgene: |
Tg(Prnp-APPSweOsa)#Luk Location: unknown
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| Alliance: |
Tg(Prnp-APPSweOsa)#Luk page
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Mutation details: The cDNA for isoform 695 of the human APP gene, engineered to contain the Swedish K670N and M671L and Osaka E693 deletion mutations, was placed under the control of the mouse prion protein promoter.
(J:282772)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:282772 Kulic L, et al., Early accumulation of intracellular fibrillar oligomers and late congophilic amyloid angiopathy in mice expressing the Osaka intra-Abeta APP mutation. Transl Psychiatry. 2012 Nov 13;2:e183 |
| All: |
2 reference(s) |
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Analysis Tools
