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Tg(Tcf-lacZ)1Baa
Transgene Detail
Summary
Symbol: Tg(Tcf-lacZ)1Baa
Name: transgene insertion 1, Benjamin A Alman
MGI ID: MGI:3795171
Synonyms: TCF-gal
Transgene: Tg(Tcf-lacZ)1Baa  Location: unknown  
Alliance: Tg(Tcf-lacZ)1Baa page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsA Tcf-reporter construct was generated containing the lacZ gene downstream of a c-Fos minimal promoter and three consensus Tcf-binding motifs. Binding of a beta-catenin-Tcf complex activates the expression of lacZ. (J:76273)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:76273 Cheon SS, et al., beta-Catenin stabilization dysregulates mesenchymal cell proliferation, motility, and invasiveness and causes aggressive fibromatosis and hyperplastic cutaneous wounds. Proc Natl Acad Sci U S A. 2002 May 14;99(10):6973-8
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory