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Gene Expression Data
Assay Details
Assay
Reference: J:152846 Szabo R, et al., Regulation of cell surface protease matriptase by HAI2 is essential for placental development, neural tube closure and embryonic survival in mice. Development. 2009 Aug;136(15):2653-63
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6392083
Gene symbol: Spint2
Gene name: serine protease inhibitor, Kunitz type 2
Reporter: lacZ
Direct Detection
Results
Specimen 4A: embryonic day 7.5; Spint2Gt(KST272)Byg/Spint2+ (more )
Structure Level Pattern Image Note
TS11: embryo Present Diffuse 4A
TS11: future brain neural fold Present 4A

Specimen 4B: embryonic day 8.0; Spint2Gt(KST272)Byg/Spint2+ (more )
Structure Level Pattern Image Note
TS12: future brain Present Regionally restricted 4B Expression is at the border between the neural and non-neural ectoderm.
TS12: non-neural ectoderm Present Regionally restricted 4B Expression is at the border between the neural and non-neural ectoderm.
TS12: foregut diverticulum Present Regionally restricted 4B Expression is in the epithelium.
TS12: hindgut diverticulum Present Regionally restricted 4B Expression is in the epithelium.

Specimen 4C: embryonic day 8.5; Spint2Gt(KST272)Byg/Spint2+ (more )
Structure Level Pattern Image Note
TS13: future brain Present Regionally restricted 4C Expression is at the border between the neural and non-neural ectoderm.
TS13: non-neural ectoderm Present Regionally restricted 4C Expression is at the border between the neural and non-neural ectoderm.

Specimen 4D: embryonic day 8.5; Spint2Gt(KST272)Byg/Spint2+ (more )
Structure Level Pattern Image Note
TS13: foregut diverticulum Present Regionally restricted 4D Expression is in the epithelium.
TS13: hindgut diverticulum Present Regionally restricted 4D Expression is in the epithelium.
TS13: embryo Present Regionally restricted 4D Expression is at the caudal extremity of the embryo in the future tail region.

Specimen 4E: embryonic day 8.5; Spint2Gt(KST272)Byg/Spint2+ (more )
Structure Level Pattern Image Note
TS13: future spinal cord neural fold Present Regionally restricted 4E Expression is proximal to the region of neural tube closure.
TS13: non-neural ectoderm Present Regionally restricted 4E Expression is proximal to the region of neural tube closure.

Specimen 4F: embryonic day 8.0; Spint2Gt(KST272)Byg/Spint2+ (more )
Structure Level Pattern Image Note
TS12: trophectoderm Present Regionally restricted 4F Expression is in chorionic trophoblasts and in the underlying trophoblast cells within the labyrinth.

Specimen 4G: embryonic day 10.5; Spint2Gt(KST272)Byg/Spint2+ (more )
Structure Level Pattern Image Note
TS17: trophectoderm Present Regionally restricted 4G Expression is in chorionic trophoblasts and in the underlying trophoblast cells within the labyrinth.

Specimen 4H: embryonic day 10.5; Spint2Gt(KST272)Byg/Spint2+ (more )
Structure Level Pattern Image Note
TS17: trophectoderm Present Regionally restricted 4H Expression is in chorionic trophoblasts and in the underlying trophoblast cells within the labyrinth.

Specimen 6C: embryonic day 18.5; Spint2Gt(KST272)Byg/Spint2Gt(KST272)Byg, St14tm1Bug/St14tm1Bug (more )
Structure Level Pattern Image Note
TS26: embryo Present 6C , 6C'

Specimen not shown E9.5: embryonic day 9.5; Spint2Gt(KST272)Byg/Spint2+ (more )
Structure Level Pattern Image Note
TS15: future brain Present
TS15: tail Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory