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Gene Expression Data
Assay Details
Assay
Reference: J:139570 Capellini TD, et al., Pbx1/Pbx2 govern axial skeletal development by controlling Polycomb and Hox in mesoderm and Pax1/Pax9 in sclerotome. Dev Biol. 2008 Sep 15;321(2):500-14
Assay type: RNA in situ
MGI Accession ID: MGI:6391094
Gene symbol: Pax9
Gene name: paired box 9
Probe: Pax9 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 7A Pax9 E9.5 WT: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: somite Present 7A Pax9 E9.5 WT
Specimen 7A Pax9 E10.5 WT: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: somite Present 7A Pax9 E10.5 WT
Specimen 7A Pax9 E10 Pbx1-/-;Pbx1-/- (left): embryonic day 10.0; Pbx1tm1Mlc/Pbx1tm1Mlc, Pbx2tm1Mlc/Pbx2tm1Mlc (more )
Structure Level Pattern Image Note
TS16: somite Absent 7A Pax9 E10 Pbx1-/-;Pbx2-/- (left)
TS16: tail unsegmented mesenchyme Trace 7A Pax9 E10 Pbx1-/-;Pbx2-/- (left) Low levels of expression most caudally in pre-somitic mesoderm.
Specimen 7A Pax9 E10 Pbx1-/-;Pbx1-/- (right): embryonic day 10.0; Pbx1tm1Mlc/Pbx1tm1Mlc, Pbx2tm1Mlc/Pbx2tm1Mlc (more )
Structure Level Pattern Image Note
TS16: somite Absent 7A Pax9 E10 Pbx1-/-;Pbx2-/- (right)
TS16: tail unsegmented mesenchyme Trace 7A Pax9 E10 Pbx1-/-;Pbx2-/- (right) Low levels of expression most caudally in pre-somitic mesoderm.
Specimen 7C WT: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present 7C WT
TS19: hindlimb bud Present 7C WT
TS19: somite Present 7C WT
Specimen 7C Pbx1-/-;Pbx2+/-: embryonic day 11.5; Pbx1tm1Mlc/Pbx1tm1Mlc, Pbx2tm1Mlc/Pbx2+ (more )
Structure Level Pattern Image Note
TS19: forelimb bud Weak 7C Pbx1-/-;Pbx2+/- Expression reduced in anterior forelimb and hindlimb buds.
TS19: hindlimb bud Weak 7C Pbx1-/-;Pbx2+/- Expression reduced in anterior forelimb and hindlimb buds.
TS19: somite Weak Regionally restricted 7C Pbx1-/-;Pbx2+/- Expression down-regulated in differentiating somites.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory