Pax1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:139570 Capellini TD, et al., Pbx1/Pbx2 govern axial skeletal development by controlling Polycomb and Hox in mesoderm and Pax1/Pax9 in sclerotome. Dev Biol. 2008 Sep 15;321(2):500-14
Assay type:	RNA in situ
MGI Accession ID:	MGI:6391093
Gene symbol:	Pax1
Gene name:	paired box 1

Probe:	CX10
Probe preparation:	Antisense labelled with digoxigenin RNA

Results

Specimen 7A Pax1 E9 WT: embryonic day 9.0 (more

)

Structure	Level	Pattern	Image	Note
TS14: somite	Present		7A Pax1 E9 WT

Specimen 7A Pax1 E9.5 WT: embryonic day 9.5 (more

)

Structure	Level	Pattern	Image	Note
TS15: somite	Present		7A Pax1 E9.5 WT

Specimen 7A Pax1 E10.5 WT: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: somite	Present		7A Pax1 E10.5 WT

Specimen 7A Pax1 E10.5 Pbx1-/-;Pbx1-/-: embryonic day 10.5; Pbx1^tm1Mlc/Pbx1^tm1Mlc, Pbx2^tm1Mlc/Pbx2^tm1Mlc (more

)

Structure	Level	Pattern	Image	Note
TS17: somite	Absent		7A Pax1 E10.5 Pbx1-/-;Pbx2-/-

Specimen 7A Pax1 E10.75 Pbx1-/-;Pbx1-/-: embryonic day 10.75; Pbx1^tm1Mlc/Pbx1^tm1Mlc, Pbx2^tm1Mlc/Pbx2^tm1Mlc (more

)

Structure	Level	Pattern	Image	Note
TS17: somite	Absent		7A Pax1 E10.75 Pbx1-/-;Pbx2-/-

7B WT ©

Specimen 7B WT: embryonic day 11.5 (more

)

Structure	Level	Image
TS19: forelimb bud	Present	7B WT
TS19: hindlimb bud	Present	7B WT
TS19: somite	Present	7B WT

7B WT FL ©

Specimen 7B WT FL: embryonic day 11.5 (more

)

Structure	Level	Pattern	Image	Note
TS19: sclerotome	Present		7B WT FL

7B WT HL ©

Specimen 7B WT HL: embryonic day 11.5 (more

)

Structure	Level	Pattern	Image	Note
TS19: sclerotome	Present		7B WT HL

Specimen 7B Pbx1-/-;Pbx2+/-: embryonic day 11.5; Pbx1^tm1Mlc/Pbx1^tm1Mlc, Pbx2^tm1Mlc/Pbx2⁺ (more

)

Structure	Level	Pattern	Image	Note
TS19: forelimb bud	Weak		7B Pbx1-/-;Pbx2+/-	Expression down-regulated in forelimb;.
TS19: hindlimb bud	Absent		7B Pbx1-/-;Pbx2+/-	Expression absent from proximal hindlimb.
TS19: somite	Present	Regionally restricted	7B Pbx1-/-;Pbx2+/-	Expression down-regulated in lumbar-sacral domains. Expression spatially restricted to caudal somites.

Specimen 7B Pbx1-/-;Pbx2+/- FL: embryonic day 11.5; Pbx1^tm1Mlc/Pbx1^tm1Mlc, Pbx2^tm1Mlc/Pbx2⁺ (more

)

Structure	Level	Pattern	Image	Note
TS19: sclerotome	Present	Diffuse	7B Pbx1-/-;Pbx2+/- FL	Expression spatially diffuse in sclerotome.

Specimen 7B Pbx1-/-;Pbx2+/- HL: embryonic day 11.5; Pbx1^tm1Mlc/Pbx1^tm1Mlc, Pbx2^tm1Mlc/Pbx2⁺ (more

)

Structure	Level	Pattern	Image	Note
TS19: sclerotome	Present	Diffuse	7B Pbx1-/-;Pbx2+/- HL	Expression spatially diffuse in sclerotome.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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